BioVision-Immuno checkpoint mediated PD-1 and PD-L1 tools

BioVision-Immuno checkpoint mediated PD-1 and PD-L1 tools

2018.03.09

 

 

PD-1/PD-L1- Immune Checkpoint Blockade for Cancer Immunotherapy

Programmed death 1 (PD-1) is an immune checkpoint receptor expressed on several immune cells, particularly cytotoxic T cells. PD-1 has a prominent role in modulating T-cell activity in peripheral tissues via interaction with its ligands, PD-L1 (B7-H1, CD274) and PD-L2 (B7-DC). The interaction of PD-1 with PD-L1 and PD-L2 inhibits T-Cell proliferation, survival and cytokine production, hence escaping immune responses and preventing autoimmunity. Blocking interaction between PD1 and its ligands is an effective method for reversing cancer immunosuppression and thereby promoting immune responses against several cancer types. BioVision offers a comprehensive collection of products, including proteins, ELISA kits and many more tools to support Immune check point research. 

Fig.1A. (Cat. No. 7498) SDS-PAGE (4-20%) of Recombinant Human PD-1: 2μg Human PD-1 recombinant protein loaded under reducing conditions and stained with Coomassie Blue. Fig.1B. Biological activity(Cat. No. 7498).  Immobilized Human PD-1, His Tag at 5μg/mL (100 μL/well) can bind Human PD-L1, His Tag with a linear range of 0.15-1.25 μg/mL

Below are some of the products we offer for PD-1 and PD-L1 research:

 

Category

Product Name

Cat. No.

Size

Specification

Antibodies

Anti-PD-1 (Nivolumab), Humanized Antibody

A1307

100 μg

Human

Anti-PD-1 (Pembrolizumab), Humanized Antibody

A1306

100 μg

Human

Anti-PD-1 Antibody

A1384

30 μg, 100 μg

Human

Anti-PD-L1 (Atezolizumab), Humanized Antibody

A1305

100 μg

Human

Anti-PD-L1 Antibody

A1454

30 μg, 100 μg

Human

 

 

 

 

 

 

Recombinant Proteins

CD274, mouse recombinant

7311

100 μg

Mouse

 Human CellExpTM PD-L1 /CD274 /B7-H1, human recombinant

7429

10 μg, 50 μg

Human

Human CellExpTM Biotinylated PD-1 / PDCD1, His Tag & Fc Tag, human recombinant

7877

5 μg

Human

Human CellExpTM PD-1 /PDCD1, C-Fc Tag, human recombinant

7500

10 μg, 50 μg

Human

Human CellExpTM PD-1 /PDCD1, C-Fc Tag, mouse recombinant

7503

10 μg, 50 μg

Mouse

Human CellExpTM PD-1 /PDCD1, human recombinant

7498

10 μg, 50 μg

Human

Human CellExpTM PD-1 /PDCD1, mouse recombinant

7499

10 μg, 50 μg

Mouse

Human CellExpTM PD-L1 /CD274 /B7-H1, mouse recombinant

7428

10 μg, 50 μg

Mouse

Human CellExpTM CD273 / B7-DC / PD-L2, human recombinant 

7369

10 μg, 50 μg

Human

PDCD1LG2, human recombinant

7337

50 μg

Human

PD-1/PDCD1, Human Recombinant

P1024

10 μg, 50 μg

Human

Human CellExpTM PD-1 / PDCD1 Protein, mouse recombinant

P1086

10 μg, 50 μg

Mouse

Human CellExpTM PD-1/PDCD1, C-Fc+His Tag, Human recombinant

P1264

10 μg, 50 μg

Human

Biotinylated PD-1/PDCD1, Human Recombinant

P1038

10 μg, 50 μg

Human

ELISA Kits

PD-L1/CD274 (Human) ELISA Kit

K4155

100 assay

Human

PD-1 (human) ELISA Kit

K4153

100 assay

Human

BioSimTM anti-Pembrolizumab (Keytruda®) (Human) ELISA Kit

E4397

100 assay

Human

BioSimTM anti-Nivolumab (Opdivo®) (Human) ELISA Kit

E4396

100 assay

Human

BioSimTM Pembrolizumab (Keytruda®)(Human) ELISA Kit

E4383

100 assay

Human

BioSimTM Nivolumab (Opdivo®)(Human) ELISA Kit

E4382

100 assay

Human

TEL:+886-2-88663366   FAX:+886-2-28331789   MAIL:info@abscience.com.tw

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