Greetings from Cosmo Bio, Tokyo. The summer is leaving and the fall is coming. But still we have some hot days last week. During the span of the changing seasons, it is said that we often get cold. Please take care of yourself and enjoy our products and e-mail news!
In this E-mail NEWS, we introduce to you our NEW PRODUCTS!
COSMO BIO NEW PRODUCTS!
HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus (1). The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells (2). It is also involved in the endocytosis and degradation of cell surface receptor proteins such as CD4 and MH4 which are important for AIDS virus infection.
Purified full-size recombinant Nef of HIV-1 subtype B expressed in E. coli
Western blot (1/1,000~1/3,000)
Dot blot (1/3000)
Immunoprecipitation (assay dependent)
ELISA (assay dependent)
2. accura-expRACE KIT (BIG Price Down!)
*US patent #7504240
Japanese patent #4304350
1st-strand cDNA synthesis ⇒ 2nd-strand cDNA synthesis ⇒RACE PCR