ANTI HUMAN SHP
PP-N7519-00
1
Brand
Iwai North America
Description
SHP (NR0B2) is an orphan receptor. SHP is expressed in liver and at lower level in heart, adrenal gland, spleen and pancreas. Since SHP binds to several receptors, including retinoid receptors RAR, RXR and thyroid hormone receptor, the function is suggested as a negative regulator of receptor-dependent signaling pathways.
Application
WB
Reactivity