Cynomolgus Transferrin R / CD71 Protein, His Tag

Source : 

Cynomolgus Transferrin R, His Tag (TFR-C524a) is expressed from human 293 cells (HEK293). It contains AA Cys 89 – Phe 760 (Accession # XP_005545315.1).

Molecule : Transferrin R

Synonyms : CD71,TFRC,TFR,sTfR,TfR1,Trfr,T9,p90

Format : Powder

Category : Bio-Markers & CD Antigens

Accession : XP_005545315.1

Storage : -20℃

Shipping condition : Powder,RT

Molecular Weight : 77.1 kDa

Characteristics :

This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 77.1 kDa. The protein migrates as 75-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

Buffer : PBS, pH7.4

Description :

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

References :

(1) Aisen P., 2004, Int. J. Biochem. Cell Biol. 36 (11): 2137–43.
(2) Moos T., 2002, Danish Medical Bulletin 49 (4): 279–301.