His6-UbcH3 (Cdc34)
E2-610
50 μg 100 μg
Brand
Boston Biochem
Description
His6-UbcH3 (Cdc34)
Catalog #: E2-610
His6-UbcH3 (Cdc34)
Product Source:
human recombinant
UbcH3 plays an essential role in the progression of cells from the G1 to S phase of the cell division cycle. One pathway (requiring Cdc34) initiates DNA replication by degrading a CDK (cyclin-dependent kinase) inhibitor. The second pathway, involves the anaphase-promoting complex (APC) initiates chromosome segregation and exit from mitosis by degrading anaphase inhibitors and mitotic cyclins.
Application
Reactivity
