Paxillin (LD4 Motif), Rabbit Antibody

ZZZZ_Status (Active, Disc) : Active

AA_Supplier Name : Biosensis

Alternative_Name (Other Names) :

PXN

Antibody_Isotype
(Antibody only) : IgGkappa

Application_Details :

This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Background_Info :

Clone_Name
(AB only, monoclonals) : LD4 sAB

Datasheet_Link :

Description (Long Description) : 

This full-length, chimeric rabbit antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques. This antibody binds to the LD4-motif of human paxillin, a signal transduction adaptor protein involved in focal adhesion, with binding partners including integrins, Src, FAK or actin complexes. The antibody inhibits complex formation between paxillin and FAK. Paxillin is involved in both inside-out cell signalling and outside-to-inside cell signalling.

Expiry_Date : 

12 months after purchase if unopened.

Format (Form) : 

Liquid, PBS with 0.02% Proclin 300.

Immunogen (Antigen) :Peptide corresponding to human paxillin-LD4 motif (residues 260-278) fused to MBP; peptide sequence: WGGSATRELDELMASLSD.

Kit_Components :

MSDS (File name) :