AntibodiesRabbit antibody to ATG16 L1: whole serum

PDF

R-158-100

100 µL

Brand

biosensis

Description

ZZZZ_Status (Active, Disc) : Active

 

AA_Supplier Name : Biosensis

 

Alternative_Name (Other Names) :

Autophagy-related protein 16-1; APG16-like 1; ATG16L1

 

Antibody_Isotype
(Antibody only) : Mixed

 

Application_Details :

Non-reduced western blot: 1:100; IP: 1-50-1:100 (5-10uL/500uL lysate); ELISA: 1:2000-1:3000 direct detection only, recombinant immunogen.

 

Background_Info :

 

Clone_Name
(AB only, monoclonals) :

 

Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=230

 

Description (Long Description) : 

ATG16 L1 plays an essential role in autophagy. It is a homooligomer ant interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). APG16 L1 localises to the cytoplasm, in particularly to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. There are 5 named isoforms produced by alternative splicing. Genetic variation within ATG16 L1 are associated with susceptibility to inflammatory bowel disease type 1.

 

Expiry_Date : 

Six months after purchase

 

Format (Form) : 

Lyophilized

 

Immunogen (Antigen) :N-terminal of human ATG16-L1 protein conjugated to Blue Carrier Protein has been used as the immunogen.

 

Kit_Components :

 

MSDS (File name) :

 

Application

ELISAICCWBD

Reactivity

HumanRat

Photos