Rabbit antibody to ATG16 L1: whole serum
R-158-100
100 µL
Brand
biosensis
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Autophagy-related protein 16-1; APG16-like 1; ATG16L1
Antibody_Isotype
(Antibody only) : Mixed
Application_Details :
Non-reduced western blot: 1:100; IP: 1-50-1:100 (5-10uL/500uL lysate); ELISA: 1:2000-1:3000 direct detection only, recombinant immunogen.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=230
Description (Long Description) :
ATG16 L1 plays an essential role in autophagy. It is a homooligomer ant interacts with ATG5. Part of either the minor and major complexes respectively composed of 4 sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1 (800 kDa). APG16 L1 localises to the cytoplasm, in particularly to preautophagosomal structure (PAS) where it is involved in the membrane targeting of ATG5. There are 5 named isoforms produced by alternative splicing. Genetic variation within ATG16 L1 are associated with susceptibility to inflammatory bowel disease type 1.
Expiry_Date :
Six months after purchase
Format (Form) :
Lyophilized
Immunogen (Antigen) :N-terminal of human ATG16-L1 protein conjugated to Blue Carrier Protein has been used as the immunogen.
Kit_Components :
MSDS (File name) :
Application
ELISAICCWBD
Reactivity
HumanRat