Rabbit polyclonal antibody to Connexin-43 (366-382): Affinity purified
R-1607-100
100 µg
Brand
biosensis
Description
ZZZZ_Status (Active, Disc) : Active
AA_Supplier Name : Biosensis
Alternative_Name (Other Names) :
Cx43; gap junction alpha-1 protein; GJA1; GJAL; Gap junction 43 kDa heart protein;
Antibody_Isotype
(Antibody only) :
Application_Details :
Immunohistochemistry (IHC) and Western Blotting (WB). A concentration of 0.1-0.5 µg/mL is recommended for WB. The predicted length of human Connexin-43 is 382 residues and MW of 43 kDa. A concentration of 0.5-1.0 µg/mL is recommended to detect Connexin-43 in formalin fixed and paraffin embedded tissues. Heat mediated antigen retrieval is required. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
Background_Info :
Clone_Name
(AB only, monoclonals) :
Datasheet_Link : http://www.biosensis.com/pdf_datasheet.php?products_id=1203
Description (Long Description) :
A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexins, through which materials of low molecular weight diffuse from one cell to a neighbouring cell. Each connexin is composed of a hexamer of connexin proteins. Connexins are a multi-gene family of highly related proteins. At least a dozen distinct connexin genes have been identified and many are expressed in a tissue-specific manner. Two distinct lineages, class I (beta) and class II (alpha), have been identified in mammals. Connexin-43, also known as Gap junction alpha-1 (GJA1), belongs to the class II (alpha) group of connexins and is expressed in the heart and foetal cochlea.
Expiry_Date :
12 months after purchase
Format (Form) :
Lyophilized with 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
Immunogen (Antigen) :A synthetic peptide corresponding to the amino acids 366-382 from the C-terminus of human Connexin-43.
Kit_Components :
MSDS (File name) :
Application
IH,FrozenIH(P), ParaffinWB
Reactivity
HumanMouseRat