Rat NGAL ELISA Kit

Brand

BIOPORTO

Description

NGAL (neutrophil gelatinase-associated lipocalin)1
belongs to the lipocalin family of proteins2
. These
are secreted proteins characterized by i) their ability
to bind small hydrophobic molecules in a structurally
conserved pocket formed by β-pleated sheet, ii)
to bind to speci c cell-surface receptors, and iii) to
form macromolecular complexes. NGAL has many
synonyms: perhaps the most widely used is lipocalin
2 (LCN 2); more recently the name siderocalin has
been used to express NGAL’s ability to bind bacterial
siderophores3
. In the rat, NGAL was rst named 25
kDa α2
-microglobulin-related protein4
, and later neurelated
lipocalin (NRL)5
because of its expression in
mammary tumors initiated by the neu (HER2/c-erbB-2)
oncogene. In the mouse, the homologous protein is
known as oncogene protein 24p36
, 24-kDa superinducible
protein (SIP24) or uterocalin7

Application

Reactivity

Photos