UbcH9

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E2-645

50 μg 100 μg

Brand

Boston Biochem

Description

UbcH9

Catalog #: E2-645

UbcH9
Product Source: 

human recombinant

UbcH9 is a member of the E2 family and is homologous to ubiquitin-conjugating enzymes, but is specific for the conjugation of SUMO to a variety of target proteins. This E2 is unusual in that it interacts directly with protein substrates that are modified by SUMOylation, and may play a role in substrate recognition. UbcH9 can mediate the conjugation of SUMO-1, SUMO-2 and SUMO-3 to a variety of proteins including RanGAP1, IκBα, and PML without the requirement of an E3 ligase.

Product Information
Quantity: 

50 μg 100 μg

Stock: 

X mg/ml (X μM) in 50 mM HEPES pH 7.6, 125 mM NaCl, 10% glycerol, 1 mM DTT. Actual concentration will vary with specific lot number.

MW: 

20 kDa

Purity: 

> 95% by SDS-PAGE

 

Use & Storage
Use: 

Typical enzyme concentration to support conjugation in vitro is 100 nM-1 μM depending on conditions.

Storage: 

Store at -80°C. Avoid multiple freeze/thaw cycles.

Application

Reactivity

Photos

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