Proteins and PeptidesVibrio cholerae serotype O1 CTXB Protein, His Tag

PDF

CTB-V52E8

50ug

Brand

ACROBiosystems

Description

Source

Vibrio cholerae serotype O1 CTXB, His Tag (CTB-V52E8) is expressed from human 293 cells (HEK293). It contains AA Thr 22 – Asn 124 (Accession # P01556).

 

Molecule : CTXB

 

Synonyms : CTXB,TOXB

 

Format : Powder

 

Category : Other Recombinant Proteins

 

Accession : N/A

 

Storage : -20℃

 

Shipping condition : Powder,RT

 

Molecular Weight : 13.5 kDa

 

Characteristics :

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 13.5 kDa. The protein migrates as 18-22 kDa under reducing (R) condition (SDS-PAGE).

 

Endotoxin Level : Less than 1.0 EU per μg by the LAL method.

 

Buffer : PBS, pH7.4

 

Description :

Cholera enterotoxin subunit B (CTXB) is also known as cholera enterotoxin B chain, cholera enterotoxin gamma chain and choleragenoid. Vibrio cholerae O1 exists as two major serotypes, Inaba and Ogawa, which are associated with the O antigen of the lipopolysaccharide and are capable of unequal reciprocal interconversion. The B subunit pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. CTXB can bind five GM1 gangliosides. Also, it has no toxic activity by itself.

 

References :

(1) Lockman H., et al., 1983, J. Biol. Chem. 258:13722-13726.
(2) Fujinaga Y., et al., 2003, Mol. Biol. Cell 14:4783-4793.

Application

Reactivity

Photos