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Reagents for Untangling AD Mechanism
Alzheimer’s disease (AD) is the most common form of dementia for people over 65 years of age. AD is associated with formation of amyloid plaques and neurofibrillary tangles in the brain. Numerous cellular pathways are investigated for early diagnosis, treatment and symptoms management. Abbiotec offers over 200 antibodies, peptides and proteins for studying the detection, progression, treatment, and cell signaling events associated with AD. Browse our catalog for rabbit, mouse and rat antibodies that are developed for ELISA, western blot, IHC and immunofluorescence applications.
Download our Alzheimer’s Disease Product Brochure here.
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Amyloid Plaques
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Alpha-Synuclein, APP, Beta-Amyloid [1-42], [1-40], [1-16], [1-28], ERAB, Fe65
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Biomarkers
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ApoE, Aromatase, ChAT, CHRM1, GFAP, NMDAR, NTP, PSD-95
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Growth Factors &
Receptors
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NGF, NGFR, TGF-beta 1/2/3, TGF-beta Receptors I/II, TrkA/B/C, Tyro 3, VEGF, VEGFR1/2/3
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Inflammation
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AGE, CD Markers, G-CSF, Interleukins, M-CSF, TNF-alpha, TNFR, RAGE
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Neurofibrillary Tangles
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NF H/L/M, Tau, phospho-Tau, Tubulins alpha/beta/gamma
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Neuroprotection
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ADNP, BDNF, Col VI, Galanin, Gelsolin, HSP25, 27, 40, 60, 70, 90 Substance P, Substance P Receptor
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Oxidation
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HO-1, NOS-1/2/3, SOD 1/2
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Phosphorylation
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Cdk5, GSK3b, PKN2, PP1, PP2A/B, PTEN
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Proteases
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BACE, Calpain 1, 2, 3, 5, 6, 9, 10, Caspase 1, 3, 6, 8, 9, 10, Notch1/2, Presenilin-1
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Signaling
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AKT-1/2/3, Beta-catenin, phospho-AKT1, PI3KCA, PI3KC3, SMAD1/2/4, STAT3, TRADD, phospho-Synapsin 1/2/3, Synaptotagmin
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Peptides
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Autocamtide-2, Beta-Amyloid [1-42], [1-40], [25-35], Calcineurin Autoinhibitory, Calcineurin Substrate, Cathepsin L Substance, CREBtide, Kemptide, Protein Kinase C [19-35], Ser25 PKC [19-31], Substance P, Tyrosine Proteine Kinase Substrate
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Proteins
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NGF-beta, VEGF, VEGFR
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Contact our Customer Service Dept for comprehensive listing, availability, and new products to be released.
SPECIAL OFFER – Until October 31, 2020 – Save 10% on Alzheimer’s Disease Antibodies, Proteins and Peptides. Use promo code ENEWS0920 at time of order. Terms and conditions apply.
LATEST PRODUCT CITATIONS – For a complete list of product citations, refer to the citation webpage.
Cat. No. 250761 MTR-1 Antibody for IHC in rat brain tissues
Kang NH. et al. 2016. Brain Res. PMID 27693415. Altered melatonin MT1 receptor expression in the ventral midbrain following 6-hydroxydopamine lesions in the rat medial forebrain bundle.
Cat. No. 250922 Beta-Amyloid [1-28] Antibody and Cat. No. 350017 Beta Amyloid [1-42] Peptide for immunomagnetic biosensor applied to AD diagnosis.
Li S-S. et al. 2016. Nature. PMID 27112198. Non-invasive screening for early Alzheimer’s disease diagnosis by a sensitively immunomagnetic biosensor.
Cat. No. 251900 TNF-alpha Antibody for WB in rat brain
Mulas G. et al. 2016. Exp Neurol. PMID 27697481. Differential induction of dyskinesia and neuroinflammation by pulsatile versus continuous I-DOPA delivery in the 6-OHDA model of Parkinson’s disease.
Cat. No. 254515 Beclin-1 (Ser15) Antibody for WB in rat hippocampal neurons
Hwang J-Y. et al. 2017. Cell Death Differ. PMID 27935582. Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die.
Cat. No. 350130 Corazonin Peptide for behavior assay in ants
Gospocic J. et al. 2017. Cell. PMID 28802044. The neuropeptide corazonin controls social behavior and caste identity in ants.
ABBIOTEC is a biotech company founded in 2007 in San Diego, California, a renowned world-class Life Sciences cluster that hosts more than 1,500 research labs and biotech companies. We are focused on developing, producing and commercializing next generation antibodies and unique reagents for the Life Sciences research community including the diagnostic and pharmaceutical markets.
ABBIOTEC offers years of expertise making antibodies and assay kits for catalog products to the scientific and biotech community. With our USDA-certified animal facility, we offer polyclonal antibody production in small and large animals (rabbits, goats, llama) as well as monoclonal antibody production (mice and rats) and antibody libraries (mice and llamas). Because peptide chemistry is an essential tool to biology, we offer custom peptide synthesis services for research-grade peptides.
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