Serological tests can be used to identify whether people have been exposed to a particular pathogen by looking for the presence of antibodies that are produced in response to infections. The demand for serological tests of SARS-CoV-2 is increasing rapidly in order to improve the accuracy of clinical diagnosis and better quantify the number of cases of COVID-19, including those that may be asymptomatic or have recovered.
Serological test kits that are approved by FDA include colloidal gold immunoassay, chemiluminescence immunoassay and ELISA. S1 protein, RBD protein and N protein are the main antigens used in commercial anti-SARS-CoV-2 antibody detection kits.
ACROBiosystems has developed SARS-CoV-2 S1, RBD and N proteins with different tags including His, Fc, mFc and His&Avi. We also offer 5+ mutant types of RBD proteins. The formulation of S1, RBD and N proteins are customized to be well suited for colloidal gold immunoassay, chemiluminescence immunoassay and ELISA to assist the diagnosis of COVID-19.
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