ACRO | 專為新冠病毒 (COVID-19) 血清測試開發而設計的蛋白質

ACRO | 專為新冠病毒 (COVID-19) 血清測試開發而設計的蛋白質

2020.05.20

 【專為新冠病毒 (COVID-19) 血清測試開發而設計的蛋白質】

SARS-CoV-2 S1, RBD and N proteins for serological test development

 

Serological tests can be used to identify whether people have been exposed to a particular pathogen by looking for the presence of antibodies that are produced in response to infections. The demand for serological tests of SARS-CoV-2 is increasing rapidly in order to improve the accuracy of clinical diagnosis and better quantify the number of cases of COVID-19, including those that may be asymptomatic or have recovered.

Serological test kits that are approved by FDA include colloidal gold immunoassay, chemiluminescence immunoassay and ELISA. S1 protein, RBD protein and N protein are the main antigens used in commercial anti-SARS-CoV-2 antibody detection kits.

ACROBiosystems has developed SARS-CoV-2 S1, RBD and N proteins with different tags including His, Fc, mFc and His&Avi. We also offer 5+ mutant types of RBD proteins. The formulation of S1, RBD and N proteins are customized to be well suited for colloidal gold immunoassay, chemiluminescence immunoassay and ELISA to assist the diagnosis of COVID-19.

 

 

Product: SARS-CoV-2 (COVID-19) Nucleocapsid protein, His Tag
Cat. No.: NUN-C51H9

 

The sensitivity of N protein binding to Anti-N mAb is 0.02 ng/mL as verified by ELISA.

Immobilized SARS-CoV-2 Nucleocapsid protein, His Tag (Cat. No. NUN-C51H9) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 NP Antibody, Rabbit MAb (CLN27) with a linear range of 0.02-0.3 ng/mL.

Free Protocol >>

 

Product: SARS-CoV-2 (COVID-19) S1 protein, His Tag (MALS verified)
Cat. No.: S1N-C52H4

 

The sensitivity of S1 protein binding to ACE2 protein is 0.2 ng/mL as verified by ELISA.

Immobilized SARS-CoV-2 S1 protein, His Tag (Cat. No. S1N-C52H4) at 2 μg/mL (100 μL/well) can bind Human ACE2, Fc Tag (Cat. No. AC2-H5257) with a linear range of 0.2-6 ng/mL.

Free Protocol >>

 

Product: SARS-CoV-2 (COVID-19) ) S protein RBD, His Tag (MALS verified)
Cat. No.: SPD-C52H3

 

The sensitivity of RBD protein binding to ACE2 protein is 0.008 ng/mL as verified by ELISA.

Immobilized Human ACE2, Fc Tag (Cat. No. AC2-H5257) at 2 μg/mL (100 μL/well) can bind SARS-CoV-2 S protein RBD, His Tag (Cat. No. SPD-C52H3) with a linear range of 0.008-0.125 μg/mL.

Free Protocol >>

 

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