用於實體瘤研究的高酶活性的FAP均二聚體
Choosing the FAP Homodimer with High Enzyme Activity for Solid Tumor Study
FAP is a promising therapeutic target for solid tumor due to its unique enzymatic activity and selective expression in tumor microenvironment, which is enzymatically active as a homodimer.
ACROBiosystems has developed a series of active FAP homodimer protein products. The homodimer purity, binding capacity and enzyme activity have been verified by SEC-MALS, ELISA and enzyme assay respectively, and the specific enzyme activity is greater than 8000 pmol/min/µg.
Assay Data
>> The specific enzyme activity is greater than 8000 pmol/min/µg.
Measured by its ability to convert the substrate benzyloxycarbonyl-Gly-Pro-7-amido-4-methylcoumarin (Z-GP-AMC) to Z-Gly-Pro and 7-amino-4-methylcoumarin (AMC). The specific activity is >8000 pmol/min/µg.
>> The homodimer purity of human FAP was verified by SEC-MALS
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The purity of Human FAP, His Tag (MALS verified) (Cat. No. FAP-H5244) was more than 95% and the molecular weight of this protein is around 180-195 kDa verified by SEC-MALS. |
>>> Human FAP can bind anti-FAP (Sibrotuzumab) antibody with a linear range of 0.1-2 ng/mL
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Immobilized Human FAP, His Tag (Cat. No. FAP-H5244) at 1 μg/mL (100 μL/well) can bind Anti-FAP (Sibrotuzumab) Antibody, Human IgG1 with a linear range of 0.1-2 ng/mL |
Product List
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