Alpha-Synuclein: A Key Target for Parkinson’s Disease Therapies
Alpha-synuclein (α-syn) aggregates into toxic fibrils in Parkinson’s disease (PD), disrupting neuronal function and causing neuronal cell death. We provide premium α-syn-related products to support your research and advance PD drug development.
TREM2: A Promising Target for Neurological Disorders
TREM2 on microglial cells clears neurotoxic amyloid-β (Aβ) and regulates neuroinflammation, crucial in Alzheimer’s disease and other neurodegenerative disorders. As a ligand, APOE interacts with TREM2, influencing disease pathology. We offer high-quality TREM2, Aβ, APOE, and other neuroscience proteins to support therapeutics development.
Sortilin: Key Protein in Neurodegeneration and Inflammation Research
Sortilin is a multifunctional membrane protein implicated in neurodegenerative diseases like Alzheimer’s (AD) and Parkinson’s (PD). It supports neuronal growth and repair by binding ligands like NGF and BDNF, while also regulating neuroinflammation through pro-inflammatory cytokine modulation. Additionally, Sortilin influences lipid metabolism, contributing to diseases like atherosclerosis. We offer Sortilin protein and stable cell lines for research into neurodegeneration neuroinflammation, and lipid metabolism disorders.
