ACRO | 想為您的BsAb發育找到1:1異源二聚體中更純淨的CD3蛋白嗎?聯繫我們 立即獲取免費樣品!

ACRO | 想為您的BsAb發育找到1:1異源二聚體中更純淨的CD3蛋白嗎?聯繫我們 立即獲取免費樣品!

2020.12.31

ACRO | 想為您的BsAb發育找到1:1異源二聚體中更純淨的CD3蛋白嗎?聯繫我們 立即獲取免費樣品!

CD3-targeted therapeutic antibody usually recognizes the CD3ε in the heterodimer complex to activate the anti-tumor activity of T cells. However, in the process of recombinant expression, CD3E and CD3D can randomly form incorrect heterogeneous complexes, leading to the loss of bioactivity and high batch-to-batch inconsistency.

ACROBiosystems has developed a series of confirmed homogeneous CD3δ/CD3ε and CD3γ/CD3ε proteins with good bioactivity.

·    Purer 1:1 heterodimers verified by non-reducing electrophoresis and MALS

·    Show good performance in different applications in therapeutic antibody development

·    Used for the development of a bispecific antibody in clinical phase successfully

Free sample is available! Try it Now!

Product List

>>> Click to find out more CD3 proteins.

Assay Data

>>> Purer 1:1 heterodimer verified by non-reducing electrophoresis and MALS

Fig.1 Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. CDD-H52W1) on SDS-PAGE under reducing (R) and non-reducingNRcondition. The purity of the protein was more than 85% and around 35-43 kDa verified by SEC-MALS.

>>> High bioactivity and batch-to-batch consistency