ACRO | 想為您的BsAb發育找到1：1異源二聚體中更純淨的CD3蛋白嗎？聯繫我們 立即獲取免費樣品！
CD3-targeted therapeutic antibody usually recognizes the CD3ε in the heterodimer complex to activate the anti-tumor activity of T cells. However, in the process of recombinant expression, CD3E and CD3D can randomly form incorrect heterogeneous complexes, leading to the loss of bioactivity and high batch-to-batch inconsistency.
ACROBiosystems has developed a series of confirmed homogeneous CD3δ/CD3ε and CD3γ/CD3ε proteins with good bioactivity.
· Purer 1:1 heterodimers verified by non-reducing electrophoresis and MALS
· Show good performance in different applications in therapeutic antibody development
· Used for the development of a bispecific antibody in clinical phase successfully
Free sample is available! Try it Now!
>>> Click to find out more CD3 proteins.
>>> Purer 1:1 heterodimer verified by non-reducing electrophoresis and MALS
Fig.1 Human CD3E&CD3D Heterodimer Protein, His Tag&Tag Free (Cat. No. CDD-H52W1) on SDS-PAGE under reducing (R) and non-reducing（NR）condition. The purity of the protein was more than 85% and around 35-43 kDa verified by SEC-MALS.
>>> High bioactivity and batch-to-batch consistency