Finding purer CD3 proteins in 1:1 heterodimer for your BsAb development? Get the free sample now!
CD3-targeted therapeutic antibody usually recognizes the CD3ε in the heterodimer complex to activate the anti-tumor activity of T cells. However, in the process of recombinant expression, CD3E and CD3D can randomly form incorrect heterogeneous complexes, leading to the loss of bioactivity and high batch-to-batch inconsistency.
ACROBiosystems has developed a series of confirmed homogeneous CD3δ/CD3ε and CD3γ/CD3ε proteins with good bioactivity.
· Purer 1:1 heterodimers verified by non-reducing electrophoresis and MALS
· Show good performance in different applications in therapeutic antibody development
· Used for the development of a bispecific antibody in clinical phase successfully
Free sample is available! Try it Now!