ACRO | 提供獨特的天然折疊生物素化CD19蛋白來染色CAR-T細胞

ACRO | 提供獨特的天然折疊生物素化CD19蛋白來染色CAR-T細胞

2020.11.10

 

Finding an Exclusive Native Folded Biotinylated CD19 Protein for Staining CAR-T cells

It is an important topic for therapeutic monoclonal antibodies to optimize the antibody structure and obtain the ideal antibody with affinity to Fc receptor. Therefore, high-quality Fc receptors are indispensable in the development of antibody drugs.

ACROBiosystems offers more than 50 Fc receptors with different molecules, species, tags and biotin conjunction to help expedite your mAb development.

Free sample is available! Try it Now!

Based on the Biacore T200/8K platform and ForteBio Octet platform, ACROBiosystems provides SPR /BLI analytical services to our valued customers.

>>>> Click to learn more about the SPR/BLI analytical service.

>>>> Contact with our scientist

Features

·    High purity, bioactivity and batch-to-batch consistency

·    SPR/BLI verified and protocol offered for free

·    Biotinylated ones are available

Product List

What customers say about the products :

Assay Data

>>> High Purity

Fig.1 Human CD32a (R167), His Tag (BLI verified) on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

>>> Bioactivity validated by SPR&BLI

> SPR

> BLI

Fig. 2 Human CD64, His Tag (SPR & BLI verified) (Cat. No. FCA-H52H1) captured on CM5 chip via anti-His antibody can bind Herceptin with an affinity constant of 4.92 nM as determined in a SPR assay (Biacore 8K)

Fig.3 Loaded Human FCGRT&B2M Heterodimer Protein, His Tag (SPR & BLI verified) (Cat. No. FCN-H52W7) on SA Biosensor via Biotin his antibody, can bind Herceptin with an affinity constant of 0.14 μM as determined in BLI assay (ForteBio Octet Red96e).

>>> High Batch-to-batch Consistency

Fig. 4 Batch consistency of Human Fc gamma RIIB / CD32b (Cat. No. CDB-H5228). The consistency of different batches is more than 90%.

>>> Biotinylated CD16a and more

Get SPR/BLI service

Fig. 5 Biotinylated Human CD16a (V176), His Tag, Avi Tag (Cat. No. CDA-H82E9) captured on Biotin CAP- Series S Sensor Chip can bind Rituximab with an affinity constant of 0.261 μM as determined in a SPR assay (Biacore T200).

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