ACROBiosystems |了解抗SLAMF7 CAR-T細胞療法的新出版物,並免費試用PE-SLAMF7蛋白!

ACROBiosystems |了解抗SLAMF7 CAR-T細胞療法的新出版物,並免費試用PE-SLAMF7蛋白!

2021.01.22

本文轉載自原廠電子報: ACROBiosystems | www.acrobiosystems.com

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Learn New Publications of Anti-SLAMF7 CAR-T Cell Therapy, and Try PE- SLAMF7 Protein for Free!

 

 

On October 8, 2020, a study has been published in Nature communications indicated that T cells expressing a CD28-containing anti-SLAMF7 CAR and a suicide switch capable of eliminating CAR T cells on demand exhibit increased anti-tumor activity and decreased toxicity.

 

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Researchers from University of California-Los Angeles find that BCMA/CS1 single-chain bispecific CAR-T cells exhibit superior CAR expression and function compared to T cells that co-express individual BCMA and CS1 CARs. The BCMA/CS1 bispecific CAR presents a promising treatment approach to prevent antigen escape in CAR-T cell therapy against MM.

 

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The newly launched PE-labeled SLAMF7 protein (Cat. No. SL7-HP2H3)

at ACROBiosystems is a powerful tool for detecting anti-SLAMF7 CAR expression by one step staining with high sensitivity and high specificity. Besides PE-labeled version, FITC and Biotin-labeled SLAMF7 proteins are also available. The bioactivity of these products has been verified by flow cytometry.

 

Request for free sample

 

 

 

 

Validation Data by FACS

 

ProductPE-Labeled Human SLAMF7 Protein, His Tag

Cat. NoSL7-HP2H3

 

 

 

 

 

 

1e6 of the anti-SLAMF7 CAR-293 cells were stained with 100 μL of 1:50 dilution (2 μL stock solution in 100 μL FACS buffer of PE-Labeled Human SLAMF7 Protein, His Tag (Cat. No. SL7-HP2H3)

and negative control protein respectively, PE signals was used to evaluate the binding activity (QC tested).

Protocol

 

 

 

ProductFITC-Labeled Human SLAMF7, His Tag

Cat. NoSL7-HF2H7

 

 

 

 

 

2e5 of Anti-SLAMF7 CAR-293 cells were stained with 100 μL of 10 μg/mL of FITC-Labeled Human SLAMF7, His Tag (Cat. No. SL7-HF2H7

) and negative control protein respectively, FITC signal was used to evaluate the binding activity (QC tested)

Protocol

 

 

 

 

 

 

Product list

 

MoleculeSLAMF7

 

 

 

 

Related moleculeBCMA

 

 

 

 

 

> Click here to learn more about targets of CAR-T cell therapy

 

 

> Click here to learn more about BCMA protein

 

 

>Click here to learn more about mAb for anti-CD19FMC63CAR detection-flow cytometry validated

 

 

 

 

PepTalk 2021: The Protein Science and Production Week

 

 

 

 

Time: Jan 19-21, 2021, PST

 

PepTalk: Where the Protein Science Community Comes To Life

 

While a lot has changed since PepTalk was launched in 2001, the number one goal has always been the same – to serve and unite the biotherapeutics community.

 

As Peptalk celebrates 20th year, a fully integrated virtual event for 2021 will continue to serve as a content hub for the latest research and biotherapeutics developments, provide a 1:1 networking platform, offer an interactive exhibit hall, live Q&A sessions, breakout

 

Register Here

 

 

 

ACRO’s talk

 

Day One: January 19 at 1:50 p.m. PST.

Tittle: When science gets lucky: Targeting Spike protein for effective vaccine and therapeutics against SARS-CoV-2

 

Program/Track:  Protein &Antibody Therapeutics – Hindsight Is 2020: Application of Accelerated Vaccines and Therapeutics Development

 

 

Highlights:

The global SARS-CoV-2 pandemic has challenged healthcare systems around the world even after almost a year of efforts to contain spread and treat patients. One of the brightest spots has been the record pace of scientific and medical discoveries that have led to generation of promising vaccines and antibody therapeutic against SARS-CoV-2 centered on Spike protein (S). ACROBiosystems is proud to support development of vaccines and therapeutics against COVID-19.

 

Secure Your Spot

 

 

 

 

Meet Our Speaker

 

 

 

Prajwal Paudel, Ph.D.

 

Product Development Scientist 

at ACROBiosystems 

 

 

We are doing a raffle for our llamas. Click here

 to enter our raffle and have the chance to win an adorable & plushy Llama! We will contact you within 5 days after the event if you win the llama.

 

 

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