ACROBiosystems | 全民減重總動員:減重核心靶點與相關產品療法介紹

ACROBiosystems | 全民減重總動員:減重核心靶點與相關產品療法介紹

2025.08.14

 

肥胖已成為全球性的重大健康挑戰,其形成與生活方式及膳食結構的轉變密切相關。肥胖問題不僅影響體態外觀,更是糖尿病、心血管疾病、癌症、神經退行性疾病及心理健康問題的重要風險因素,給公共衛生系統帶來沉重負擔。面對這一涉及多方面的健康危機,深入探究肥胖的病因學及調控機制,或為開發針對相關併發症的有效治療幹預措施奠定科學基礎。

 

https://www.bmisurgery.com/health-risks-tied-to-obesity-2

與肥胖相關的健康風險 – BMI指數

 

 

 

ACROBiosystems百普賽斯針對減重病理機制中的核心靶點,構建了覆蓋GLP-1RGCGRGIPRGPR75GDF-15FGF-21Activin
R
的重組蛋白、功能細胞株等產品,全面助力減重相關靶向藥物及療法開發。

 

 

驗證資料

 

GLP-1R蛋白:親和力經SPR驗證

 

GLP1R
agonist captured on Protein A Chip can bind Human GLP1R Full Length Protein,
Flag, His Tag (Cat. No. GLR-H52D4)
with an affinity constant of 2.74 µM as determined in a SPR assay (in presence
of DDM and CHS) (Biacore 8K) (Routinely tested).

 

Activin RIIB蛋白:親和力經SPR驗證

 

Biotinylated
Human Activin RIIB Protein, His,Avitag (Cat. No. ACB-H82E3)
immobilized on CM5 Chip can bind Human Latent Activin A, His Tag (Cat. No. ACA-H424x) with an affinity constant of 0.147
nM as determined in a SPR assay (Biacore 8K) (Routinely tested).


 

GIPR穩定細胞株:高生物活性經FACS驗證

 

Flow cytometry surface staining of human GIPR on
HEK293/Human GIPR Stable Cell Line (Cat. No. CHEK-ATP206, High Expression) demonstrates
consistent mean fluorescent intensity across passage 8-23.

GDF-15蛋白:高生物活性經ELISA驗證

 
 

 

Immobilized
Human GFR alpha-like, His Tag (Cat. No. GFA-H52H3)
at 5 μg/mL (100 μL/well) can bind Human GDF-15, Fc Tag (Cat. No. GD5-H5269) with a linear range of 0.1-6 ng/mL
(QC tested).


 

 

Follow Us On

LinkedIn
Youtube


back-Top
open-line

LINE 線上諮詢

亞旭-LINE-QRcode

掃瞄或手機直接點擊條碼

error: Content is protected !!