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The overall solution for antibody and Fc receptor affinity testing- ACROBiosystems
Based on the Biacore T200/8K platform and ForteBio Octet platform, ACROBiosystems provides SPR /BLI analytical services to our valued customers. The SPR/BLI analytical services include antibody screening, antibody pairing/group, kinetic analysis, and interaction measurement.
Platforms
>>> Surface Plasmon Resonance (SPR) service
>>> Biolayer Interferometry (BLI) service
Promotion
The overall solution for antibody and Fc receptor affinity testing
All Fc receptor proteins needed are free of charge
Only provide analytes, then get the full service
Case study
>>> Fc receptor protein affinity testing
Herceptin &Human Fc gamma RI / CD64（SPR analytical service）
Fig 1. Human CD64, His Tag (SPR & BLI verified) immobilized on CM5 Chip via an anti-His antibody, can bind to Herceptin with an affinity constant of 5.45 nM as determined in a SPR assay (Biacore T200).
Herceptin &Human Fc gamma RI / CD64（BLI analytical service）
Fig 2. Human CD64, His Tag (SPR & BLI verified) loaded on HIS1K Biosensor, can bind to Herceptin with an affinity constant of 13 nM as determined in a BLI assay (ForteBio Octet Red96e).
>>> Large molecule affinity testing
Fig 3. Trastuzumab can bind to C1q with an affinity constant of 3.24 nM as determined in BLI assay (ForteBio Octet Red96e).
Fig 4. Herceptin immobilized on CM5 Chip can bind C1q with an affinity constant of 46.5 nM as determined in SPR assay (Biacore T200).
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