antibodies-online offers COVID-19 Vaccine Positive Samples as well confirmed Positive and Negative Samples that are designed for use in a wide range of research applications.
The Single Donor Human SARS-Cov-2 Presumptive Non-Placebo Vaccine Positive Sample is a whole blood-derived product for which the COVID-19 vaccine positive status has been confirmed via SARS-CoV-2 IgG antibody assay through negative pre-trial blood draw results and positive post booster tests.
The samples are suitable for use as a control to confirm antibody assay results as well for the development of virus neutralization tests, among other research applications.
antibodies-online offers a series of S-6P proteins
In the development of most COVID-19 vaccines, the Spike Protein was used to trigger the immune response. The structural change by the replacement of two proline amino acids in the S2 subunit of the Spike Protein (S-2P), stabilizes the trimer and keeps the protein longer in prefusion state, which leads to a stronger immune response.
Recent research results indicate that four additional proline mutations in the S2 subunit (S-6P) stabilize the structure of the trimer even more and keeps most of the protein in prefusion state. That means, S-6P shows superior bioactivity over S-2P.