How does SARS-CoV-2 evade Immune Response?
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Recent studies on SARS-CoV-2 evaluating evasion of immune response reveal several SARS-CoV-2 proteins which manipulate host response in favor of virus proliferation. Compared with other virus-related respiratory diseases, the IFN-I and IFN-III signaling is more efficiently suppressed. This ultimatively leads to low interferon-stimulated gene (ISG) responses with impact on viral transmission and pathogenesis.¹
Interferon Antagonism of SARS-CoV-2 Proteins according to Xia et al. ² Selection of Interferon Antagonism Antibodies |
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