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GroPep Bioreagents, a Biosensis Company
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Detecting IGF-ll: The Vital Role in Brain Health
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| Insulin-like Growth Factor 2 (IGF-ll) is emerging as a critical factor in synaptic plasticity and memory function. IGF-ll is abundantly expressed in the central nervous system. IGF-ll expression and function in the brain are mediated by intricate processes through the IGF-ll receptor, which is highly expressed in neurons, and have a crucial role in regulating protein trafficking, synthesis and degradation.
The detection of IGF-ll deficiencies in the brain, serum and cerebrospinal fluid is vital for studying various neurological disorders, including Alzheimer’s, Parkinson’s, depression, and anxiety. By detecting IGF-ll with specific reagents, researchers can explore the mechanisms through which IGF-ll impacts development, metabolism, and disease processes. |
| IGF-ll: Recent Study Highlights |
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| The images show IGF-ll protects SN4741 dopaminergic cells against MPP+-induced toxicity in cell cultures through Giemsa staining. Adapted from Elisa Martín-Monta et al. (2021), Redox Biology, Vol. 46, Fig. 1 |
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Explore More!
Illuminate IGF Insights with GroPep’s Advanced Reagents
GroPep Bioreagents offers a comprehensive range of IGF reagents, ideal for studying brain function and diseases.
GroPep’s recombinant proteins are ISO 9001-compliant and are perfect for exploring IGF roles in cell and tissue culture, as well as whole animal studies. Our antibodies and recombinant proteins are used for western blot, flow cytometry, or bioassay protocols. With our recently extended ISO accreditation, we can manufacture any protein or antibody you might need meeting AS/NZS ISO:9001:2016 quality standards.
Connect with our expert scientists today to discuss your IGF research needs!” |
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