Bladder Cancer Biomarkers
膀胱癌是泌尿系統最常見的惡性腫瘤之一，其中大部分是膀胱移形上皮細胞癌(Transitional cell carcinoma)，約有70%為淺表性腫瘤。在治療後5~15年內復發率為60%~85%，其中20%可能進展為侵襲性腫瘤，因此早期發現膀胱腫瘤和復發腫瘤變得十分重要。膀胱癌標記的檢測具有非侵入性、高靈敏、特異性高等特點，已成為膀胱癌早期診斷的重點。
Cloud clone提供多種膀胱癌檢測標記蛋白、抗體及ELISA試劑盒，可用於檢測人、小鼠、大鼠、豬、山羊等。
1. Cloud-Clone膀胱癌檢測標記相關指標性產品
|
Cloud-Clone related index products of Bladder cancerdetection markers |
||
|
ApoA1 |
Ki-67/MKI67 |
EpCAM/TROP1 |
|
IL-8/CXCL8 |
MMP-9 |
|
2. Cloud-Clone優質膀胱癌生物標記產品文獻引用列表（部分列表）
|
Item |
Species |
Journals |
IF |
Pubmed ID |
Institute |
|
ApoA1 |
Mouse |
Cell Metabolism |
20.565 |
27866837 |
Department of Molecular Genetics, CARIM, Maastricht University |
|
ApoA1 |
Mouse |
6.854 |
26279300 |
Molecular and Cellular Biology Laboratory, Division of Basic Sciences, University of Crete Medical School, Greece |
|
|
Human |
Cellular Physiology and Biochemistry |
5.5 |
27160777 |
Department of Gynecologic Oncology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University |
|
|
MMP9 |
Human |
Cellular Physiology and Biochemistry |
5.5 |
29224019 |
National Key Laboratory of Cancer Invasion Research, National Center for Digestive Diseases |
|
Human |
Journal of Molecular and Cellular Cardiology |
5.296 |
28088561 |
Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China. |
|
|
EpCAM |
Human |
Microchemical Journal |
2.746 |
(GENYO) Universidad de Granada |
|
|
Ki67 |
Human |
Chemistry & Biodiversity |
1.617 |
29874411 |
Department of Cancer Biology National Cancer Institute, Cairo University, Egypt |
- 3. Cloud-Clone膀胱癌生物標記相關SCI引用統計(節選)
Matrix Metalloproteinase 9 (MMP9)
|
Product |
Species |
SCI Citations |
|
Human, Rat, Mouse, Rabbit, Cattle, Sheep, Simian |
128 |
|
|
1. Li P, Sun Y, Liu Q. MicroRNA-340 induces apoptosis and inhibits metastasis of ovarian cancer cells by inactivation of NF-κB1[J]. Cellular Physiology and Biochemistry, 2016, 38(5): 1915-1927.（IF=5.5） 2. Bai Z, Wang J, Wang T, et al. The MiR-495/annexin A3/P53 axis inhibits the invasion and EMT of colorectal cancer cells[J]. Cellular Physiology and Biochemistry, 2017, 44(5): 1882-1895.（IF=5.5） 3. Yoshizaki K, Brito J M, Silva L F, et al. The effects of particulate matter on inflammation of respiratory system: Differences between male and female[J]. Science of the Total Environment, 2017, 586: 284-295. 4. Li P, Sun Y, Liu Q. MicroRNA-340 induces apoptosis and inhibits metastasis of ovarian cancer cells by inactivation of NF-κB1[J]. Cellular Physiology and Biochemistry, 2016, 38(5): 1915-1927. 5. Moustafa P E, Abdelkader N F, El Awdan S A, et al. Liraglutide ameliorated peripheral neuropathy in diabetic rats: Involvement of oxidative stress, inflammation and extracellular matrix remodeling[J]. Journal of neurochemistry, 2018. |
||
Interleukin 8 (IL8)
|
Product |
Species |
SCI |
|
Protein / Antibody / ELISA kit |
Human, Rat, Mouse, Rabbit, Pig, Cattle, Chicken, Sheep, Horse |
92 |
|
Excerpts： 1. Luo J Y, Li X M, Zhou Y, et al. Mutant DD genotype of NFKB1 gene is associated with the susceptibility and severity of coronary artery disease[J]. Journal of molecular and cellular cardiology, 2017, 103: 56-64.（IF=5.296） 2. Wang A, Wang F, Yin Y, et al. Dexamethasone reduces serum level of IL-17 in Bleomycin-A5-induced rats model of pulmonary fibrosis[J]. Artificial cells, nanomedicine, and biotechnology, 2018, 46(4): 783-787. 3. Jackson C J, Reppe S, Eidet J R, et al. Optimization of Storage Temperature for Retention of Undifferentiated Cell Character of Cultured Human Epidermal Cell Sheets[J]. Scientific Reports, 2017, 7(1): 8206. 4. Cui Y, Pi X, Wang C, et al. Effects of different ventilation strategies on exhaled nitric oxide in geriatric abdominal surgery[J]. Journal of breath research, 2015, 9(1): 016006. 5. Pagani S, Borsari V, Veronesi F, et al. Increased Chondrogenic Potential of Mesenchymal Cells From Adipose Tissue Versus Bone Marrow‐Derived Cells in Osteoarthritic In Vitro Models[J]. Journal of cellular physiology, 2017, 232(6): 1478-1488. |
||
Apolipoprotein A1 (APOA1)
|
Product |
Species |
SCI Citations |
|
Protein / Antibody / ELISA kit |
Human, Rat, Mouse, Rabbit, Pig |
31 |
|
Excerpts： 1. Van Der Vorst E, Theodorou K, Wu Y, et al. High density lipoproteins exert pro-inflammatory effects on macrophages via passive cholesterol depletion and PKC-NF-kB/STAT1-IRF1 signaling[J]. Atherosclerosis, 2017, 263: e6.（IF=20.565） 2. Gkouskou K K, Ioannou M, Pavlopoulos G A, et al. Apolipoprotein AI inhibits experimental colitis and colitis-propelled carcinogenesis[J]. Oncogene, 2016, 35(19): 2496.（IF=6.854） 3. Wittenberg M, Nassiri M, Francuzik W, et al. Serum levels of 9α, 11β‐PGF 2 and apolipoprotein A1 achieve high predictive power as biomarkers of anaphylaxis[J]. Allergy, 2017, 72(11): 1801-1805.（IF=6.048） |
||
