Cancer Biomarkers in Clinical Practice
癌症生物標記是由腫瘤或組織物分泌而來分子， 其中一些物質在正常體內是不存在的，只存在於胚胎中； 一些物質在正常人體內表達值較低，僅在腫瘤患者中高表現。 經過百年的研究，許多研究發現數百種癌症生物標記。 但到目前為止，在診斷中發揮特定作用的生物標記還很少， 大多數癌症生物標記只能作為輔助指標，只有幾十種生物標記在腫瘤診斷、臨床治療、復發轉移等方面具有重要意義。
Cloud-Clone可以提供多種蛋白質、抗體和廣泛癌症生物標記ELISA試劑盒，可用於檢測人、小鼠、大鼠、豬、山羊等物種樣品。
1. Cloud-Clone 癌症生物標記熱門品項
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Cloud-Clone related index products of Broad-Spectrum Cancer Biomarkers |
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AFP |
NR3A1 |
PSA |
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AMACR |
NR3A2 |
NR3C3 |
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MUC16 |
Her2 |
Tk1 |
2. Cloud-Clone 優質生物標記相關產品文獻引用列表 (部分列表)
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Item |
Species |
Journals |
IF |
Pubmed ID |
Institute |
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AFP |
Human |
EBioMedicine |
6.183 |
30045829 |
Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-sen University; Guangdong Provincial Key Laboratory of Liver Disease Research, Guangzhou, China. |
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NR3A1 |
Human |
Cellular Physiology and Biochemistry |
5.5 |
29975948 |
Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China. |
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NR3A2 |
Mouse |
Molecular Neurobiology |
5.076 |
26476840 |
Department of Experimental Neuroendocrinology, Institute of Pharmacology, Polish Academy of Sciences |
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PSA |
Rat |
4.414 |
19716283 |
Department of Pharmacology, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea. |
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TK1 |
Human |
Molecular Imaging and Biology |
3.626 |
27324368 |
Molecular Imaging Center Antwerp (MICA), Faculty of Medicine and Health Sciences, University of Antwerp |
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CA125 |
Mouse |
PLoS One |
2.806 |
27755542 |
Department of Nephrology, University of Heidelberg, Heidelberg, Germany. |
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Her2 |
Mouse |
Neuroscience Letters |
2.159 |
21539896 |
Department of Histoembryology, Mu Dan Jiang Medical College |
3. Cloud-Clone癌症檢測指標相關SCI引用統計(節選)
Alpha-Fetoprotein (AFP)
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Product |
Species |
SCI Citations |
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Protein / Aantibody / ELISA kit |
Human, Rat, Mouse, Rabbit, Bovine, Caprine, Simian |
51 |
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Excerpts: 1. Xie Z, Zhou F, Yang Y, et al. Lnc-PCDH9-13: 1 Is a Hypersensitive and Specific Biomarker for Early Hepatocellular Carcinoma[J]. EBioMedicine, 2018, 33: 57-67.（IF=6.183） 2. Hu T, Wang Z, Lv P, et al. One-pot synthesis of a highly selective carboxyl-functionalized superparamagnetic probes for detection of alpha-fetoprotein[J]. Sensors and Actuators B: Chemical, 2018, 266: 270-275.（IF=5.667） 3. Mansour M A, Bekheet S A, Al‐Rejaie S S, et al. Ginger ingredients inhibit the development of diethylnitrosoamine induced premalignant phenotype in rat chemical hepatocarcinogenesis model[J]. Biofactors, 2010, 36(6): 483-490. 4. Kumar R S, Murugananthan G, Rajkapoor B. Anticarcinogenic potential of ethanol extract of Indigofera cordifolia Roth.(Fabales: Fabaceae) on diethylnitrosamine induced hepatocarcinogenesis in rats[J]. Brazilian Journal of Biological Sciences, 2017, 4(7): 53-66. 5. Hassoun S M, Abdel-Rahman N, Eladl E I, et al. Antiangiogenic activity of vitexicarpine in experimentally induced hepatocellular carcinoma: Impact on vascular endothelial growth factor pathway[J]. Tumor Biology, 2017, 39(6): 1010428317707376. |
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Estrogen Receptor Beta (NR3A2)
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Product |
Species |
SCI Citations |
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Protein / Aantibody / ELISA kit |
Human, Rat, Mouse |
12 |
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Excerpts: 1. Rzemieniec J, Litwa E, Wnuk A, et al. Selective aryl hydrocarbon receptor modulator 3, 3′-diindolylmethane impairs AhR and ARNT signaling and protects mouse neuronal cells against hypoxia[J]. Molecular neurobiology, 2016, 53(8): 5591-5606.（IF=5.076） 2. Rzemieniec J, Litwa E, Wnuk A, et al. Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERβ or GPR30 signalling[J]. The Journal of steroid biochemistry and molecular biology, 2015, 146: 26-37.（IF=4.095） 3. Liu X, Liu H, Xiong Y, et al. Postmenopausal osteoporosis is associated with the regulation of SP, CGRP, VIP, and NPY[J]. Biomedicine & Pharmacotherapy, 2018, 104: 742-750. |
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Estrogen Receptor Alpha (NR3A1)
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Product |
Species |
SCI Citations |
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Protein / Aantibody / ELISA kit |
Human, Rat, Mouse |
11 |
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Excerpts: 1. Hao J, Jin Z, Zhu H, et al. Antiestrogenic activity of the Xi-Huang formula for breast cancer by targeting the estrogen receptor α[J]. Cellular Physiology and Biochemistry, 2018, 47(6): 2199-2215.（IF=5.5） 2. Kajta M, Wnuk A, Rzemieniec J, et al. Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling[J]. The Journal of steroid biochemistry and molecular biology, 2017, 171: 94-109.（IF=4.095） 3. Nacken W, Wixler V, Ehrhardt C, et al. Influenza A virus NS1 protein‐induced JNK activation and apoptosis are not functionally linked[J]. Cellular microbiology, 2017, 19(7): e12721. |
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