Lentivirus is a subfamily of the retrovirus family. Lentiviruses can deliver a significant amount of genetic information into host cells and integrate it into the cellular genome. The recombinant lentivirus system has been remarkably improved to embrace more unique advantages. Lentiviral vectors are now widely used in basic biology and translational studies for stable transgene overexpression, persistent gene silencing, immunization, transgenic animals, stem cell modifications, and much more. Besides, as most retroviruses cannot productively infect non-dividing cells, the ability to infect cells regardless of their proliferation status makes lentiviruses particularly attractive for human gene therapy.
As a leader in lentiviral technology, Creative Biogene has developed a comprehensive library of human, mouse, and rat genes cloned into lentiviral vectors or ready-to-use lentivirus. They can be used to manipulate the expression of your gene of interest within a wide range of host cells. Our comprehensive lentiviral solutions include ready-to-use particles that can be used in cell culture, in vivo studies, and plasmid clones expressing ORF, miRNA, shRNA, and sgRNA. We also offer lentivirus expression plasmid with desired promoters or tags.