Synthetic mRNA can be engineered to transiently express proteins rapidly and safely since transnuclear localization and integration into the host cell genome are not needed. And with the development of In Vitro Transcription (IVT) technique, various modified nucleotides (for example 5-methylcytidine, 5-methoxyuridine, and pseudouridine) can be simply incorporated into the synthetic mRNA to improve the immunogenicity or stability of the resulting mRNA. Therefore, synthetic mRNA has become exceedingly popular among a broad range of potential applications, such as regenerative medicine, basic cell biology, treatment of diseases, and reprogramming of cells. As a leading biotech service provider, Creative Biogene can provide worldwide researchers with high-quality raw materials and ready-to-use universal kits to synthesize mRNAs.
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