Register to Attend
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| Neurodegenerative Functions
of Microglia in Alzheimer’s Disease |
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Creative Biolabs Webinar
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Explore a neurodegenerative subset of microglia induced by cellular stress signaling that accelerates the progression of AD. |
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REGISTER
NOW |
10 AM EDT,
September 18, 2025 |
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| What’s Our Upcoming Webinar About? |
| The brain’s primary immune cells, microglia, are a leading causal cell type in Alzheimer’s disease (AD). Yet, the mechanisms by which microglia can drive neurodegeneration remain unresolved. Ayata lab discovered that a conserved stress signaling pathway, the integrated stress response (ISR), characterizes a subset of microglia with neurodegenerative outcomes. |
| Creative Biolabs has invited Dr. Pinar Ayata to walk us through the neurodegenerative functions of microglia in AD. |
Key webinar
highlights: |
- Autonomous activation of ISR in microglia.
- The ISR activation promotes the secretion of toxic lipids by microglia.
- Microglial ISR activation exacerbates neurodegenerative pathologies and synapse loss in AD models.
- Pharmacological inhibition of ISR or lipid synthesis mitigates synapse loss in AD models.
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Discover the
speaker: |
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Pinar Ayata, Ph.D.
Assistant Professor of Biology and Biochemistry
Neuroscience Initiative, Advanced Science Research Center
CUNY Graduate Center
Pinar’s most recent manuscript in Nature (provisionally accepted) from her postdoctoral work reveals the transcriptional basis of a protective subset of microglia that slows down in AD progression. Pinar opened her lab in 2020 during the height of COVID, and her lab recently discovered a neurodegenerative subset of microglia induced by cellular stress signaling that accelerates the progression of AD.
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REGISTER
NOW |
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Meet Us at the Upcoming Events |
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- August 27–29, 2025 | 5th Oligonucleotides for CNS Summit
- September 9–11, 2025 | 16th Annual World Bispecific Summit
- September 23–25, 2025 | 7th Exosome Based Therapeutic Development Summit
- September 23–27, 2025 | KSBB-AFOB Conference 2025
- October 20–22, 2025 | Antibody Engineering & Therapeutics (Asia) 2025
- November 3–6, 2025 | 16th Annual World ADC San Diego
- November 11–13, 2025 | 17th PEGS Europe Protein & Antibody Engineering Summit
- December 14–17, 2025 | Antibody Engineering & Therapeutics (US) 2025
Explore our event page to find the exciting events where you can catch up with the Creative Biolabs team!
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| Creative Biolabs is a leading figure in bringing one-stop, cutting-edge technology and products to neuroscience research. We pride ourselves on a full coverage of antibodies, proteins, cell lines, culture tools, and modulators, along with custom services that cover every angle of the neuroscience field, tailoring every aspect to fit your exact project needs. |
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