Creative Diagnostics | 有效檢測double-stranded RNA(dsRNA)工具

Creative Diagnostics | 有效檢測double-stranded RNA(dsRNA)工具

2022.07.22

 

 

Effective Tools for Double-stranded RNA (dsRNA) Detection

Creative Diagnostics 目前可提供了一套抗dsRNA的單株抗體,可用於 RNA 病毒 dsRNA 中間體的體外檢測和診斷研究,此外這些試劑也有助於 RNAi 研究,並可能用於基因治療。
這些抗體已經過驗證並通過品質檢測,具有高親和力和特異性,能靈活地同時檢測具有不同標記的 dsRNA。

 

Cat No.

Product Name

Application

CPBT-LL018

Anti-dsRNA Monoclonal Antibody, Clone K1 [Mouse IgG2a]

ELISA, IHC, dsRNA-Immunoblotting, Immunoaffinity Chromatography

Show higher affinity to poly(I)-poly(C) than other dsRNA antigens

CABT-CS603

Anti-dsRNA Monoclonal Antibody, Clone K2 [Mouse IgM]

ELISA, IHC, DB

Isotype alternative to CPBT-LL016 & CPBT-LL018
Recommended for ELISA

CPBT-LL016

Anti-dsRNA Monoclonal Antibody, Clone J2 [Mouse IgG2a]

ELISA, IHC, dsRNA-Immunoblotting, Immunoaffinity Chromatography

Recognize all naturally occurring dsRNAs
Gold-standard for dsRNA detection
Recommended for quality control of in vitro transcribed (m)RNA

CPBT-LL017

Anti-dsRNA Monoclonal Antibody, Clone J5 [Mouse IgG2b]

ELISA, IHC, dsRNA-Immunoblotting, Immunoaffinity Chromatography

Recognize all naturally occurring dsRNAs

產品特色

高親和力:檢測樣本類型包含石蠟包埋的固定組織樣本和細胞

高特異性:與 ssRNA、ssDNA 或 dsDNA 無交叉反應

 涵蓋的廣泛應用:Immunofluorescence Microscopy, dsRNA-Immunoblotting, Immunoaffinity Chromatography, Nucleic Acid ELISA, IHC, FC, DB

不同的isotype:同時檢測具有不同標記的 dsRNA ,靈活性更高

可依照需求提供Positive control:Synthetic dsRNA (142 bp)

其它消息

 

Gene Therapy

 

After over 30 years of development, gene therapy has gradually become an important means to treat genetic diseases, infectious diseases, tumors, and other diseases, which provides more options for conditions that traditional therapies cannot solve. At the same time, the rapid development of gene editing and the accumulated experience in the application of delivery vectors have also greatly promoted the progress of gene therapy.

 

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DNA-PK Signaling Pathway

 

The DNA-dependent protein kinase (DNA-PK) is a nuclear serine/threonine-protein kinase that is activated after interacting with its target DNA. DNA-PK is a complex composed of a large catalytic subunit named the DNA-PKcs and a heterodimer of Ku proteins (Ku70/80) that is a regulatory factor.

 

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