Creative Diagnostics has established the global-leading virus-like particles (VLPs) manufacturing platform using the E. coli cell system. With years of exploration, our scientists have successfully obtained various highly purified HPV VLPs. Meanwhile, our products have widely contributed to HPV vaccine-related research.
Immunogenicity assessments in vaccine trials have focused on measuring antibody responses to the vaccine. A series of functional assays have been generated to measure antibody-mediated neutralization for papillomaviruses, while some functional assays involve highly complex animal challenges and cannot be applied for routine testing.