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World Pancreatic Cancer Day is on the third Thursday in November, raising awareness about pancreatic cancer, a malignant tumor in the pancreas, which is behind the stomach and helps with digestion and blood sugar control.
The cause of pancreatic cancer isn’t clear, but risk factors include smoking, obesity, diabetes, chronic pancreatitis, and family history. It has a poor prognosis, with a 5-year survival rate under 10%. Symptoms are often unnoticed until the cancer is advanced, earning it the “king of cancers” nickname.
Treatments include surgery, chemo, radiation, immunotherapy, and targeted therapy. Immunotherapy is a new focus, with drugs targeting IGF-1R, EGFR, HER2, VEGF, CTLA-4, and PD-1 in clinical trials.
CUSABIO offers a list of popular targets and products for pancreatic cancer research to assist in mechanism studies and drug development.
Hot Targets in Diabetes Research
<![if !supportLists]>· <![endif]>ACSL4
<![if !supportLists]>· <![endif]>AKT1
<![if !supportLists]>· <![endif]>ANXA1
<![if !supportLists]>· <![endif]>AXL
<![if !supportLists]>· <![endif]>BAG3
<![if !supportLists]>· <![endif]>CCN2
<![if !supportLists]>· <![endif]>CCR8
<![if !supportLists]>· <![endif]>CD274
<![if !supportLists]>· <![endif]>CD276
<![if !supportLists]>· <![endif]>CD3D
<![if !supportLists]>· <![endif]>CD40
<![if !supportLists]>· <![endif]>CD47
<![if !supportLists]>· <![endif]>CD8A
<![if !supportLists]>· <![endif]>CDCP1
<![if !supportLists]>· <![endif]>CDH17
<![if !supportLists]>· <![endif]>CEACAM1
<![if !supportLists]>· <![endif]>CEACAM5
<![if !supportLists]>· <![endif]>CEACAM6
<![if !supportLists]>· <![endif]>CLDN18
<![if !supportLists]>· <![endif]>CNTN4
<![if !supportLists]>· <![endif]>CSF1R
<![if !supportLists]>· <![endif]>CTLA4
<![if !supportLists]>· <![endif]>DCLK1
<![if !supportLists]>· <![endif]>DKK3
<![if !supportLists]>· <![endif]>EGFR
<![if !supportLists]>· <![endif]>ENO1
<![if !supportLists]>· <![endif]>EPHA2
<![if !supportLists]>· <![endif]>ERBB2
<![if !supportLists]>· <![endif]>ERBB3
<![if !supportLists]>· <![endif]>F3
<![if !supportLists]>· <![endif]>FOLR1
<![if !supportLists]>· <![endif]>FTH1
<![if !supportLists]>· <![endif]>GAPDH
<![if !supportLists]>· <![endif]>GCC1
<![if !supportLists]>· <![endif]>GPC1
<![if !supportLists]>· <![endif]>GPX4
<![if !supportLists]>· <![endif]>HAVCR2
<![if !supportLists]>· <![endif]>HGF
<![if !supportLists]>· <![endif]>HMOX1
<![if !supportLists]>· <![endif]>ICOS
<![if !supportLists]>· <![endif]>IER3
<![if !supportLists]>· <![endif]>IGF1R
<![if !supportLists]>· <![endif]>IL1A
<![if !supportLists]>· <![endif]>KEAP1
<![if !supportLists]>· <![endif]>LOXL2
<![if !supportLists]>· <![endif]>MELTF
<![if !supportLists]>· <![endif]>MMP9
<![if !supportLists]>· <![endif]>MSLN
<![if !supportLists]>· <![endif]>MSTN
<![if !supportLists]>· <![endif]>MTOR
<![if !supportLists]>· <![endif]>MUC1
<![if !supportLists]>· <![endif]>MUC16
<![if !supportLists]>· <![endif]>NCOA4
<![if !supportLists]>· <![endif]>NECTIN4
<![if !supportLists]>· <![endif]>NFE2L2
<![if !supportLists]>· <![endif]>NFKB1
<![if !supportLists]>· <![endif]>NT5E
<![if !supportLists]>· <![endif]>PDCD1
<![if !supportLists]>· <![endif]>SLC3A2
<![if !supportLists]>· <![endif]>SLC44A4
<![if !supportLists]>· <![endif]>SLC7A11
<![if !supportLists]>· <![endif]>TAA1
<![if !supportLists]>· <![endif]>TACSTD2
<![if !supportLists]>· <![endif]>TF
<![if !supportLists]>· <![endif]>TFRC
<![if !supportLists]>· <![endif]>TIGIT
<![if !supportLists]>· <![endif]>TNF
<![if !supportLists]>· <![endif]>TNFRSF10B
<![if !supportLists]>· <![endif]>TNFRSF9
<![if !supportLists]>· <![endif]>TP53
<![if !supportLists]>· <![endif]>VEGFA
<![if !supportLists]>· <![endif]>VSIR
<![if !supportLists]>· <![endif]>ZG16B
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