Elabscience | 來自Elabscience的COVID-19蛋白,抗體和肽

Elabscience | 來自Elabscience的COVID-19蛋白,抗體和肽

2020.09.10

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Proteinase K

The outbreak of the SARS-COV-2 (2019-nCoV) is having a huge impact all around the world.

In order to better support the research of SARS-COV-2 (2019-nCoV). Elabscience® is stepping up the research and development and production of a series of important target related products of

SARS-COV-2 (2019-nCoV), including new coronavirus associated antigen, antibody, peptide, etc.

Spike Protein

The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor, and S2 contains basic elements needed for the membrane fusion.

View more information here.

SI subunit 
667 668 
SARS.CoV 
494 527 
2019_nCoV 
508 541 
S2 subunit 
HRI 
SP NTD 
13 292 306 424 
sp NTD 
13 30s 319 437 
NTD 
(N.RBD) 
HR2 
770 
788 
788 
806 
894 
912 
966 1145 1195 1219 12SS 
HR2 TM CP 
984 1163 1213 
n 
1237 1273 
c 
RBD

Nucleocapsid Protein (N protein)

The coronavirus N protein is abundantly produced within infected cells. N protein has multiple functions, including binding to viral RNA to form the ribonucleocapsid and has also been proposed to have roles in virus replication, transcription and translation.In host cells, N proteins have been shown to cause deregulation of the cell-cycle, inhibit the production of interferon, up-regulate the production of COX2, up-regulate the activity of AP1, and induce apoptosis in serum deprived cells-of all which may have possible pathological consequences.

View more information here.

RNA binding domain 
SR rich motif 
RNA binding domain 
Dimerization domain 
NLS 
IDR 
LKR 
IDR

Membrane and Unstructural Proteins

Membrane protein and Envelope protein are the key to the efficient assembly of coronavirus.

3C-like proteinase of SARS-CoV-2 virus is a key protein in RNA replication.

Papain-like protease (NSP3) plays an important role in the precursor cleavage of various viral proteins to form a series of functional proteins needed in viral replication.

3C-like proteinase and Papain-like protease are important targets for the development of antiviral drugs, which can inhibit virus replication and reduce related mortality.

ACE2 Protein

ACE2 (Angiotensin Converting Enzyme 2) is the receptor of SARS-CoV-2 infected cells, and the infection process depends on the serine protease TMPRSS2. Blocking the interaction between S protein and ACE2 is an effective way to treat coronavirus infection.

View more information here.

SARS-CoV 
SARS-CoV-2 
ACE2 
Anhenungsprotein —Spike" 
in —spike 
TMPRSS2

Proteinase K

Proteinase K is a kind of high activity proteinase of subtilisin, which is used to degrade proteins in biological samples. It can be used to digest various proteins, and it can be used in a variety of molecular biology, cell biology and other related experiments, such as genomic DNA extraction, enzyme digestion and removal, cell permeability and so on.

Proteinase K is mainly used for the production of nucleic acid extraction kit, especially for nucleic acid extraction from samples of nucleic acid diagnosis and detection in vitro diagnosis (IVD) industry.

View more information here.

SARS-COV-2 Peptide

In view of the hot targets, the Elabscience® expert team has designed and synthesized the SARS-COV-2 (2019-nCoV) related peptide, providing comprehensive support.

View more information here.

Elabscience® SARS-COV-2 (2019-nCoV) Related Products

Proteins

Category

Abbre

Cat.No.

2019-nCoV Non-structural Protein

3C-like Proteinase Protein (His Tag)(Active)

PKSR030465

Helicase Protein (His Tag)

PKSR030466

NSP1 Protein (His Tag)

PKSR030467

NSP2 Protein (His Tag)

PKSR030468

NSP7 Protein (His Tag)

PKSR030469

NSP8 Protein (His Tag)

PKSR030470

NSP10 Protein (His Tag)

PKSR030471

Papain-Like Protease Protein (Active)

PKSR030472

Guanine-N7_meth Protein (His Tag)

PKSR030473

2019-nCoV Structural Protein

Spike Protein (RBD, mFc Tag)(Active)

PKSR030474

Spike Protein (RBD, His Tag)(Active)

PKSR030475

Spike Protein (RBD-SD1, mFc Tag)(Active)

PKSR030476

Spike Protein (RBD-SD1, sHis Tag)(Active)

PKSR030477

Spike Protein (RBD-SD1, Avi-His Tag)(Active)

PKSR030478

S1 Protein (mFc Tag)(Active)

PKSR030479

S1 Protein (Fc Tag)(Active)

PKSR030480

S1 Protein (Active)

PKSR030481

S1 Protein (His Tag)

PKSR030482

S1 Protein (CTD, sssHis Tag)

PKSR030483

Spike Protein (NTD, His Tag)

PKSR030484

Nucleocapsid Protein (His Tag)

PKSR030485

NP NTD domain (His Tag)

PKSR030486

NP CTD domain Protein

PKSR030487

Envelope Protein (His Tag)

PKSR030488

S-trimer Protein (His Tag)

PKSR030489

S2 Protein (Fc Tag)

PKSR030491

NP (Truncated) (His Tag)(Active)

PKSR030537

NP NTD domain V2(His Tag)

PKSR030538

N Protein (His Tag)

E-ELC-001

2019-nCoV Host Protein

Human ACE-2 Protein (Fc Tag)(Active)

PKSR030492

Human ACE-2 Protein (Avi-His Tag)(Active)

PKSR030493

Human ACE-2 Protein (mFc Tag)(Active)

PKSR030494

Human APN Protein (His Tag)

PKSR030495

2019-nCoV Spike Mutant Protein

Spike Protein (RBD, mFc Tag)(V367F)

PKSR030523

Spike Protein (RBD,His Tag)(V367F)

PKSR030524

Spike Protein (RBD, His Tag)(F342L)

PKSR030526

Spike Protein (RBD, His Tag)(A435S)

PKSR030528

Spike Protein (RBD, His Tag)(N354D)

PKSR030529

S1 Protein (His Tag)(D614G)(Active)

PKSR030531

S1 Protein, Biotinylated (Avi-His Tag)(Active)

PKSR030532

Spike Protein (RBD, His Tag)(G476S)(Active)

PKSR030533

Spike Protein (RBD, His Tag)(W436R)(Active)

PKSR030534

Spike Protein, Biotinylated (RBD, Avi-His Tag)(Active)

PKSR030535

Spike Protein, Biotinylated (RBD, Avi-His Tag)(Active)

PKSR030536

S1 Protein (His Tag)(D614G)(Active)

PKSR030540

S-trimer Protein (His Tag)(D614G)(Active)

PKSR030541

Antibodies

Category

Abbre

Cat.No.

2019-nCoV Spike Antibody

SARS-COV-2 Spike Monoclonal Antibody[5D0]

E-AB-V1001

SARS-COV-2 Spike Monoclonal Antibody[D001]

E-AB-V1002

SARS-COV-2 Spike Monoclonal Antibody[D003]

E-AB-V1003

SARS-COV-2 Spike S1 Monoclonal Antibody[R007]

E-AB-V1005

SARS-COV-2 Spike RBD Polyclonal Antibody

E-AB-V1006

SARS-COV-2 Spike IgG/IgM Positive Control

E-AB-V1007

SARS-COV-2 Spike Monoclonal Antibody[5e8]

E-AB-V1008

SARS-COV-2 Spike S2 Monoclonal Antibody[D001]

E-AB-V1009

SARS-COV-2 Spike S2 Polyclonal Antibody

E-AB-V1010

2019-nCoV Nucleocapsid Protein Antibody

SARS-COV-2 NP Monoclonal Antibody[6G9]

E-AB-V1011

SARS-COV-2 NP ScFv Monoclonal Antibody[4A6]

E-AB-V1012

SARS-COV-2 NP Monoclonal Antibody[M05]

E-AB-V1013

SARS-COV-2 NP Monoclonal Antibody[R001]

E-AB-V1014

SARS-COV-2 NP Polyclonal Antibody

E-AB-V1015

SARS-COV-2 NP Polyclonal Antibody

E-AB-V1016

SARS-COV-2 NP IgG/IgM Positive Control

E-AB-V1017

SARS-COV-2 NP Monoclonal Antibody[4A6]

E-AB-V1018

2019-nCoV Spike Neutralizing Antibody

2019-nCoV S-hIgG1 Neutralizing Antibody[8A5]

E-AB-V1021

2019-nCoV S-mIgG1 Neutralizing Antibody[8A5]

E-AB-V1012

2019-nCoV S-cIgG1 Neutralizing Antibody[8A5]

E-AB-V1023

2019-nCoV Spike Neutralizing Antibody[4A3]

E-AB-V1024

2019-nCoV Spike Neutralizing Antibody[5A7]

E-AB-V1025

2019-nCoV S-IgM Neutralizing Antibody[8A5]

E-AB-V1026

2019-nCoV S-IgA Neutralizing Antibody[8A5]

E-AB-V1027

SARS-CoV-2 Spike RBD Neutralizing Antibody[CB6]

E-AB-V1028

ACE2 Antibody

ACE2 Polyclonal Antibody

E-AB-12224

ACE2 Polyclonal Antibody

E-AB-70126

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