GlycoMatrix™ | 12月快報

GlycoMatrix™ | 12月快報


本月亞旭代理GlycoMatrix™12月為Lectin月,將帶給您滿滿的Lectin相關產品,如Lectin Fluorophores, Concanavalin A Lectin, Sialosignaling等等。此外也有研究指出Lectin能夠去影響SARS-CoV-2病毒與細胞結合,更多詳情請參考下列表及文章

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December 2021 Newsletter

All about lectins, for your laboratory research.

Welcome to the first of our ongoing monthly newsletters. Here you’ll be able to learn more about the products you need for research, find recent news in the field of Glycobiology, and here more about how we can help.

All of our products are for laboratory research only, read on to learn more!







Lectin Fluorophores

GlycoMatrix™ offers a wide range of affinity-purified fluorophore-conjugated lectins for glycan verification of location and transformational changes. The main fluorophores used in conjugation are Fluorescein (FITC), Texas Red, Rhodamine (TRITC), Cy3, and Cy5. We also can proceed any Alexa Fluor™ or Quasar (QSD)-conjugated lectins. Within the next two months, GlycoMatrix™ will be releasing a set Infrared-Dye conjugated lectins to complement the portfolio. Please let us know if you have further suggestions to increase our portfolio.






Concanavalin A Lectin (Con A) – Pure

Affinity purified concanavalin A (Con A) is composed of two identical subunits of 237 amino acid residues (MW: 26,000 without any cystine residues). While above pH 7 it is predominantly tetrameric, at pH 4.5 – 5.6, Con A binds two metal ions per monomer: transition metals, Mn2+ and Ca2+. Both ions are required for binding with optimum activity at a pH 7.0. Con A binds with non-reducing α-D-glucose, α-D-mannose and α-methyl-D-glucopyranoside acts as a competitive inhibitor. Con A does not have a blood group specificity.







Sialylated structures are the major cancer-associated glycan alterations, including Thomsen–Friedenreich-associated antigens, sialyl Lewis antigens, α2,6-sialylated lactosamine, and gangliosides. This is due to an altered sialyltransferase expression in cancer. The presence of aberrantly sialylated structures on cell membrane receptors generates a flow of information toward the nucleus, which can exacerbate the neoplastic phenotype. offers a variety of Lectins to detect various sylylated structures associated with cancer biomarkers.







Corona Virus & Lectins

In SARS-CoV-2 research, it has been shown that Maackia amurensis Lectin targets the ACE2 receptor. As a result, the spike protein binding is suppressed, and inflammatory mediators show decreased expression (Sheehan et. Al, 2021).

GlycoMatrix carries the following quality MAA/MAL conjugated products for research use:


21511111 – Maackia amurensis Lectin (MAL/MAA I + II), Pure

21511112 – (MAL/MAA I + II), Alkaline Phosphatase

21511113 – (MAL/MAA I + II), Biotinylated

21511122 – (MAL/MAA I +II), Cy3

21511123 – (MAL/MAA I + II), Cy5

21511115 – (MAL/MAA I + II), Ferritin

21511116 – (MAL/MAA I + II), FITC

21511117 – MAL/MAA I + II), HRP

21511118 – (MAL/MAA I + II), MangeZoom Beads

21511119 – (MAL/MAA I + II), Rhodamine (TRITC)

21511120 – (MAL/MAA I + II), Separopore

21511121 – (MAL/MAA I + II), Texas Red

21510007 – Maackia amurensis Lectin (MAL/MAA I), Pure

21510734 – (MAL/MAA I), Alkaline Phosphatase

21510080 – (MAL/MAA I), Biotinylated

21761120 – (MAL/MAA I), Cy3

21761121 – (MAL/MAA I), Cy5

21761036 – (MAL/MAA I), FITC

21510925 – (MAL/MAA I), HRP

30330088 – (MAL/MAA I), MagneZoom Beads

21761037 – (MAL/MAA I), Rhodamine (TRITC)

20120064 – (MAL/MAA I), Separopore

21761038 – (MAL/MAA I), Texas Red

21511098 – Maackia amurensis Lectin (MAL/MAA II), Pure

21511098 – (MAL/MAA II), Alkaline Phosphatase

21511100 – (MAL/MAA II), Biotinylated

21511109 – (MAL/MAA II), Cy3

21511110 – (MAL/MAA II), Cy5

21511103 – (MAL/MAA II), FITC

21511104 – (MAL/MAA II), HRP

21511105 – (MAL/MAA II), MagneZoom Beads

21511106 – (MAL/MAA II), Rhodamine (TRITC)

21511107 – (MAL/MAA II), Separopore

21511108 – (MAL/MAA II), Texas Red

A recent study made it evident that WGA inhibits infection with SARS-CoV-2 by inhibiting replication when the lectin is incubated with the virus during infection. The data from the same study indicated that the mode of action is an interaction between WGA and the viral envelope, causing neutralization of the virus. This occurs via the highly glycosylated spike proteins (Auth et. Al, 2021).

GlycoMatrix carries the following high-quality WGA products for in vitro laboratory studies:


21510011 – Triticum vulgaris (Wheat germ) Lectin ( WGA), Pure

21510746 – (WGA), Alkaline Phosphatase

21510126 – (WGA), Biotinylated

20161005 – (WGA), BlackPearl

21761148 – (WGA), Cy3

21761149 – (WGA), Cy5

21511007 – (WGA), FITC

21510937 – (WGA), HRP

21511190 – (WGA), Macrobeads

20140006 – (WGA), Microplate

20120052 – (WGA), OnePASS™ Separopore® Columns (Fast Flow)

30330051 – (WGA), OnePASS™ Separopore® Columns (Spin)

21761059 – (WGA), Rhodamine (TRITC)

20181018 – (WGA), Separopore® Lectin Ligands (4B-CL)

41900226 – (WGA), Separopore® 6B

21761060 – (WGA), Texas Red

20162029 – (WGA), MagneZoom Beads


Auth, J., Fröba, M., Große, M., Rauch, P., Ruetalo, N., Schindler, M., Morokutti-Kurz, M., Graf, P., Dolischka, A., Prieschl-Grassauer, E., Setz, C., & Schubert, U. (2021). Lectin from Triticum vulgaris (WGA) Inhibits Infection with SARS-CoV-2 and Its Variants of Concern Alpha and Beta. International journal of molecular sciences, 22(19), 10205.
Sheehan, S. A., Hamilton, K. L., Retzbach, E. P., Balachandran, P., Krishnan, H., Leone, P., Lopez-Gonzalez, M., Suryavanshi, S., Kumar, P., Russo, R., & Goldberg, G. S. (2021). Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells with potential to inhibit SARS-CoV-2 infection and COVID-19 disease progression. Experimental cell research, 403(1), 112594.







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