Cytokines include a group of proteins that are secreted primarily by the immune cell to help restrict COIVD-19. Some cytokines however, can also trigger inflammation which can be problematic.
A recent study has shown two cytokines in particular produce inflammatory cell death, which in turn causes the release of more cytokines and the issue causing inflammation; these two cytokines are Tumor Necrosis Factor (TNF)-Alpha and Interferon (IFN)-Gamma.
The finding was these cytokines paired together mirror the symptoms that one would see as a COVID-19 patient.
The study describes neutralizing antibodies against Tumor Necrosis Factor (TNF)-Alpha and Interferon (IFN)-Gamma were able to protect mice from death associated with SARS-CoV-2 infection. To learn more about this exciting discovery, please refer to the link down below.
We are excited about these advancements in the fight against COVID and offer a wide range of products related to this research and more.
In case you missed it, we recently released our SARS-CoV-2 IgG Seroconversion ELISA Kit for the qualitative determination of SARS-CoV-2 specific antibodies of IgG class in plasma or serum samples. This kit is specific to the RBD of the spike protein, ensuring high sensitivity and specificity. We also offer a recombinant version of the SARS-CoV-2 Spike Protein RBD.