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MedChemExpress (MCE) provides a wide range of life-science biochemicals, including more than 100,000 bioactive compounds, dye reagents, peptides and natural compounds for laboratory and scientific use. If you need these products, please do not hesitate to contact us via sales@MedChemExpress.com.
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CAS No.: 3034176-57-0
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Target/Research Area: STAT/Triple-Negative Breast Cancer (TNBC)
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A STAT3 inhibitor with an IC50 value of 2.13 μM.
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Induces cell apoptosis and cell cycle arrest in Docetaxel-resistant TNBC cells.
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Can be used for the research of metastatic triple-negative breast cancer (mTNBC) research.
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Solubility: DMSO: 25 mg/mL (46.52 mM; Need ultrasonic)
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CAS No.: 129716-58-1
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Target/Research Area: P-glycoprotein/Cancer
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An orally active antineoplastic agent.
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Inhibits P-glycoprotein and multidrug resistance-associated protein-1 (MDR-1).
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Has highly potent reversing effect on multidrug-resistant tumor cells.
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Solubility: DMSO: 50 mg/mL (103.82 mM; Need ultrasonic)
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CAS No.: 1061337-51-6
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Target/Research Area: Antibiotic/Infection
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An orally active pleuromutilin antibiotic with a broad-spectrum antibacterial activity.
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Inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome.
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Can be used for the research of bacterial community-acquired pneumonia.
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Solubility: DMSO: 100 mg/mL (196.96 mM; Need ultrasonic)
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MedChemExpress Natural Products
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Metabolites derived from the gut microbiota contribute to maintaining fundamental host functions, and disruptions in their production can lead to various diseases, including metabolic disorders, cardiovascular diseases, gastrointestinal diseases, neurodegenerative diseases, and cancer.
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Product Name
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Description
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Urolithin A
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Mitophagy activator; Anti-inflammatory, anti-proliferative and antioxidant properties; Inducer of autophagy and apoptosis.
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Spermidine
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Neuronal nitric oxide synthase (nNOS) inhibitor; NMDA and T4 polynucleotide kinase activator; Binds and precipitates DNA.
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Lithocholic acid
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Secondary bile acid; FXR antagonist; PXR/SXR agonist; Promotes intrahepatic cholestasis.
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Brevianamide F
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Antibacterial activity property; PI3Kα inhibitor.
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Trimethylamine N-oxide dihydrate
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TGF-β/smad2 activator; Protein stabilizer; Induces cardiac fibrosis.
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Latest Publications Citing Use of MCE Products
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Nature.
2025 Jan;637(8046):726-735.
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Nature.
2025 Mar;639(8054):438-446.
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Cell.
2025 Mar 6;188(5):1248-1264.e23
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Cancer Cell.
2025 Feb 10;43(2):269-291.e19.
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Products are for research use only and are not intended for human use. We do not sell to patients.
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