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亞旭所代理的MedChemExpress (MCE) 提供多元的高品質研究化學品和生物化學品，包括超過 30,000 種用於實驗室和科學用途的新型生物活性化合物、染劑、胜肽和天然化合物。
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CAS No.: 2711006-67-4
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Research Area: CRBN Degrader/Hetero-PROTAC
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Highly potent and selective PROTAC degrader of CRBN.
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Induces ~80% CRBN degradation at 10 nM in MM1.S cells.
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Solubility: DMSO : 170 mg/mL (172.57 mM; Need ultrasonic)
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CAS No.: 913541-47-6
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Research Area: MTP Inhibitor/Dyslipidemia
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An orally active, enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor (IC50 of 8 nM).
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Reduces postprandial lipids in rats.
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CAS No.: 1039342-24-9
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Research Area: MK2 Inhibitor/Vein Graft Disease
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A peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MAPKAPK2, MK2).
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Reduces intimal hyperplasia ex vivo and in vivo.
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Prevents vein graft intimal thickening ex vivo and in vivo.
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CAS No.: 1380716-06-2
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Research Area: Glucocerebrosidase Modulator/Gaucher Disease
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A glucocerebrosidase (GCase) modulator with an EC50 of 0.4 μM.
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An activator and non-inhibitory chaperone of glucocerebrosidase.
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Increases translocation of GCase to the lysosome in human fibroblasts.
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Solubility: DMSO : 5 mg/mL (17.22 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)
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CAS No.: 20287-37-0
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Research Area: Diuretic/Hypertension
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Orally active thiazide-like diuretic, exhibits chronic antihypertensive effect.
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Potent saluretic, has the potential for oedema and hypertension research.
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MCE Anti-Colorectal Cancer Compound Library/ MCE Children’s Drug Library
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Apoptosis Assay Kits
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細胞凋亡，可以稱為程序性的細胞死亡，是一種精準的控制、需要能量的細胞死亡過程。 誘導細胞凋亡導致一系列的生化反應發生，造成細胞形態和死亡的變化。
細胞凋亡的檢測包括與細胞marker相關的方法，如染色質聚集、DNA 斷裂、粒線體損傷、細胞表面marker如phosphatidylserine外露和細胞通透性。 MCE 提供一系列高品質的細胞凋亡檢測試劑以協助您的研究。
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