Nanoprobes | 藥物遞送的好幫手 : 12 nm Nanogold® 顆粒

Nanoprobes | 藥物遞送的好幫手 : 12 nm Nanogold® 顆粒

2025.06.10

12 nm Nanogold®

 

The next big thing

 

You now have another size choice for gold nanoparticle labeling: 12 nm Nanogold® labeling reagents. 12 nm is the perfect size for post-embedding labeling and provides a third size choice for multiple Nanogold® labeling. With the same site-selective and specific reactivity that you know from our 1.4 nm and 5 nm Nanogold®, you can make any molecule with a complementary reactive group into a 12 nm gold probe with 12 nm Sulfo-NHS-, Maleimido-, and Amino- Nanogold®

 

 

12 nm Sulfo-NHS-Nanogold® and Maleimido Nanogold® labeling reactions.  

 

 

Make 12 nm Gold Probes with any Molecule

Use Maleimido-12 nm Nanogold® to selectively label any molecule with an accessible thiol, such as a cysteine residue, or Sulfo-NHS-12 nm Nanogold® to label amines, such as N-terminal amines or lysine residues. With Amino-12 nm Nanogold®, you can label carbohydrates or carboxylic acids. 

  • Antibodies 
  • Proteins 
  • Peptides
  • Oligonucleotides – DNA, RNA and PNA
  • Surfaces
  • Nanostructured materials
  • Small molecules
  • Hormones
  • …and many more

 

 

TEM of 12 nm Nanogold, showing size monodispersity and uniform spherical morphology.

 

Features and Advantages

  • Ideal for post-embedding labeling: no need for silver or gold enhancement.
  • Expanded size choices: there’s a size for every application. Use 1.4 nm Nanogold® for high resolution molecular labeling, and larger 5 or 12 nm Nanogold® for visualization on a cellular scale. 
  • Double or triple labeling made easy: three non-overlapping sizes – 1.4 nm, 5 or 12 nm. Or, silver or gold enhance the 1.4 nm Nanogold®, then use 5 or 12 nm Nanogold® for the second target.
  • Highly monodisperse: Size variation less than 10%.
  • Molecular precision: make smaller primary probes that get the gold closer to the target.
  • Site-specific conjugation enables programmed incorporation into nanostructured materials or components of self-assembling systems.
  • Stable, soluble and biocompatible: designer coating gives solubility and biocompatible for in vivo use. No residual charge means minimal non-specific binding.
  • Straightforward conjugation: no need for extra polymers or stabilizing agents, and no salt titrations or optimization.
  • Easily enhanced (if needed): Silver or gold enhancement enlarges while retaining monodispersity – or affords super-sensitive detection for blots and optical systems.

 

 

More Details

 

 

Ordering information: 

12 nm Nanogold® reagents

Catalog number

Product name and description

Price (USD)

2425-5NMOL

12 nm Sulfo-NHS-Nanogold®

$480.00

2425A-5X1NMOL

12 nm Sulfo-NHS-Nanogold® in 5 aliquots

$530.00

2425S-1NMOL

12 nm Sulfo-NHS-Nanogold® – smaller quantity for smaller-scale reactions

$125.00

2420-5NMOL

12 nm Maleimido Nanogold®

$480.00

2420A-5X1NMOL

12 nm Maleimido Nanogold® in 5 aliquots

$530.00

2420S-1NMOL

5 nm Maleimido Nanogold® – smaller quantity for smaller-scale reactions

$125.00

2421-5NMOL

12 nm Amino-Nanogold®

$365.00

2421A-5X1NMOL

12 nm Amino-Nanogold® in 5 aliquots

$401.00

2421S-1NMOL

12 nm Amino-Nanogold® – smaller quantity for smaller-scale reactions

$100.00

2421S-1NMOL

12 nm Nanogold® particles, non-reactive

$250.00

 

 

 

For more information, contact:

Ordering and customer service
Telephone: +1 (631) 205-9490 ext 101  •  Fax: +1 (631) 205-9493
Toll-free (US and Canada): 1-877-447-6266 ext 1
Email:
nano.sales@nanoprobes.com 

Technical questions and applications support
Telephone: +1 (631) 205-9490 ext 115  •  Fax: +1 (631) 980-3608
Toll-free (US and Canada): 1-877-447-6266 ext 115
Email:
tech@nanoprobes.com

 

 

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