PhosphoSolutions 設計抗體時,免疫原選擇至關重要

PhosphoSolutions 設計抗體時,免疫原選擇至關重要



Original antibody producer passionate about providing researchers with the highest quality antibodies & customer sup

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Selecting a Unique Immunogen is Crucial in Antibody Design



Immunofluorescence of healthy iPSC-derived neurons labeled with Anti-NMDA Receptor, NR2B subunit (in green). Dr. Allison Ebert, Medical College of Wisconsin.


Our founder Mike Browning discusses the difficult road to the successful production of two of our best-selling NR2A and NR2B antibodies.



Read this great publication looking at the pre-synaptic mechanisms for synaptic deficits in Alzheimer’s disease models using 2 of our phosphospecific NMDA antibodies NR2B tyr1472 and NR2A tyr1325!


Tyrosine phosphatase PTP1B impairs presynaptic NMDA receptor-mediated plasticity in a mouse model of Alzheimer’s disease

 Zhang, L., Qin, Z., Sharmin, F., Lin, W., Ricke, K.M., Zasloff, M., Stewart, A.F. and Chen, H.H., 2021. Neurobiology of Disease, p.105402.

 Read the article


NR2B WB combo

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~180 kDa NR2A or NB2B subunit of the NMDAR respectively phosphorylated. Lanes 1/2 are labeled with NR2A Tyr1325 and Lanes 3/4 are labeled with NR2B Tyr1472. Phosphospecificity is shown in the second and fourth lane (+) where immunolabeling is completely eliminated by lysate treatment with lambda phosphatase (400 units/100uL lysate for 30 min).


What We’re Reading


Heatstroke’s Effect on the Brain


This summer has been a sizzler!! Have you ever wondered what happens to the brain during a heatstroke? Check out this article from Brain Facts describing how our body regulates the extreme heat of summer when outdoors.


Read more.

Summer sizzle




Family Integrity.

PhosphoSolutions, Antibodies Inc, Aves Labs, and ImmunoChemistry Technologies have joined together to bring the life sciences community reliable tools to power your research.

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