Adiponectin Antibody

Brand

Abbiotec

Description

Adiponectin is an adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Defects in adiponectin are the cause of adiponectin deficiency (ADPND). ADPND results in very low concentrations of plasma adiponectin. Genetic variations in adiponectin are associated with non-insulin-dependent diabetes mellitus (NIDDM), also known as diabetes mellitus type 2. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.

Application

ELISA

Reactivity

Photos