ADRB2 Antibody
251604
0.1 mg
Brand
Abbiotec
Description
The beta-2 adrenergic receptor is a G-protein coupled adrenergic receptor with 30-fold higher affinity for epinephrine than norepinephrine. Agonist binding to the beta-2 adrenergic receptor initiates signal transduction pathways via activation of adenylyl cyclases. There are numerous physiological effects of beta-2 adrenergic receptor activation, including smooth muscle relaxation, blood vessel dilation, increased heart rate, and insulin secretion. The Gly-16 allele is overrepresented in individuals affected by nocturnal asthma as compared to controls, and appears to be an important genetic factor in the expression of this asthmatic phenotype.
Application
ELISAIHC
Reactivity
CanineHumanMkMouse