Ataxin-7 Antibody

Brand

Abbiotec

Description

Spinocerebellar ataxia type 7 protein (ataxin-7) is involved in neurodegeneration. Ataxin-7 is a component of the STAGA transcription coactivator-HAT complex and is involved in CRX-dependent gene activation. Defects in ataxin-7 are the cause of spinocerebellar ataxia type 7 (SCA7), also known as olivopontocerebellar atrophy III (OPCA III or OPCA3) or olivopontocerebellar atrophy with retinal degeneration. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord.

Application

ELISA

Reactivity

HumanMouse

Photos