AntibodiesATM Antibody

PDF

200158

0.1 mg

Brand

Abbiotec

Description

Ataxia telangiectasia mutated (ATM) is a Ser/Thr protein kinase which activates checkpoint signaling upon double strand breaks, apoptosis and genotoxic stresses such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. ATM is also involved in signal transduction and cell cycle control and may function as a tumor suppressor. Defects in ATM are the cause of ataxia telangiectasia, leukemia, and lymphoma.

Application

ELISA

Reactivity

HumanMouse

Photos