Belinostat

Brand

No Brand

Description

Belinostat (PXD101) is a novel HDAC inhibitor with an IC50 of 27 nM. Belinostat (PXD101) is cytotoxic in vitro in a number of tumor cell lines with IC50s in the range 0.2-3.4 µM as determined by a clonogenic assay and induces apoptosis. This hdac inhibitor is currently under phase I/II testing in lymphoma, ovarian cancer and other solid tumors.

Application

Reactivity

Photos