Beta-Amyloid Protein Antibody

Brand

Abbiotec

Description

Amyloid beta A4 protein (beta-amyloid protein) functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Beta-amyloid protein is involved in cell mobility and transcription regulation through protein-protein interactions. Beta-amyloid protein promotes transcriptional activation through binding to APBB1-KAT5 and inhibits Notch signaling through interaction with Numb. Defects in APP are the cause of Alzheimer disease type 1 (AD1). AD1 is a familial early-onset form of Alzheimer disease. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits.

Application

ELISAWB

Reactivity

HumanMouse

Photos