CD19 (HIB19) Antibody

Brand

Abbiotec

Description

h1 class=titleCD19 (HIB19) Antibody/h1
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h4Catalog Number/h4
pstrong251063/strong/p
h4Unit/h4
pstrong2 ml/strong/p
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pnbsp;/p
Format/h4
pEach vial contains 2 ml IgG (100 tests) in PBS pH7.4, 0.1% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography./p
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h4Description/h4
pThe CD19 antibody recognizes a 95 kDa type-I transmembrane glycoprotein which is restricted to B cell antigen. CD19 antigen is expressed on normal and neoplastic B cells and also in some bone marrow cells. CD19 expression by B progenitor cells is presumably at late pro-B or early pre-B stages around the time of Ig heavy chain rearrangement. Expression persists during all stages of B cell maturation and is lost on terminal differentiation to plasma cells. CD19 antigen is also found on the follicular dendritic cells and the early cells of myelomonocytic lineage but not on normal T cells, NK cells, monocytes, granulocytes, erythrocytes and platelets. In normal peripheral blood, 8-20% of lymphocytes express CD19 antigen. CD19 antigen plays a role in regulating B cell proliferation./p
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h4Product Citations/h4
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pYang XF, Shen DC., Guan Q., et al., HIM35: a monoclonal antibody synergistically stimulating hematopoiesis. Tissue Antigens. 42(4):387/p
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h4Recommended Products/h4
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h4Alternate Names/h4
pFavaloro, E.J., Bradstock, K.F., Kabral, A., Grimsley, P., Zowtyi, H. and Zola, H. (1988). Further characterization of myeloid antigens (‘gp160,95’, ‘gp150’ and ‘gp567’): Investigation of epitope heterogenetity and non-haemopoietic distribution using panels of monoclonal antibodies belonging to CD-11b, CD-13 and CD-33. British Journal of Hematology, 69: 163-171./p
h4Accession No./h4
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h4Clonality/h4
pHIB19/p
h4Antigen/h4
pnbsp;/p
h4Application Notes/h4
pnbsp;/p
pFACS with whole blood: 100 mu;l blood + 20 mu;l antibody; FACS with cells: 10E6 cells + 20 mu;l antibody. E: 1:500-1:1,000/p
pFACS: 1:200-1:1,000/p
pIHC: 1:200-1:500/p
pIF:Use at an assay dependent concentration/p
pstrongReacts with/strongnbsp; :H/p
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h4Storage/h4
pStore at 4deg;C. Product is guaranteed 6 months from the date of shipment./p
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Application

Reactivity

Photos