CGK 733

PDF

A13191-10

10mg

Brand

AdooQ BioScience

Description

Technical details

CATALOG NUM

A13191

M. WT

555.84

FORMULA

C23H18Cl3FN4O3S

PURITY

>98%

STORAGE

at -20°C 3 years Powder

CAS NO.

905973-89-9

SYNONYMS

CGK733,CGK-733

SMILES

C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC3=CC(=C(C=C3)F)[N+](=O)[O-]

Biological Activity

CGK733 is a selective inhibitor of ATR and ATM kinases. Induces cell death in prematurely senescent breast cancer cells.

Solubility *

In vitro

DMSO

100 mg/mL (179.9 mM)

Water

<1 mg/mL (<1 mM)

Ethanol

<1 mg/mL (<1 mM)

* <1 mg/ml means slightly soluble or insoluble.

* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass

1 mg

5 mg

10 mg

0.1 mM

17.99 mL

89.95 mL

179.91 mL

0.5 mM

3.6 mL

17.99 mL

35.98 mL

1 mM

1.8 mL

9 mL

17.99 mL

5 mM

0.36 mL

1.8 mL

3.6 mL

*The above data is based on the productmolecular weight 555.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

 

Application

Reactivity

Photos