CHRNA4 Antibody

Brand

Abbexa

Description

After binding acetylcholine, the neuronal acetylcholine receptor (CHRNA4) responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in CHRNA4 are the cause of nocturnal frontal lobe epilepsy type 1 (ENFL1), also symbolized ADNFLE. ENFL1 is an autosomal dominant epilepsy characterized by nocturnal seizures with hyperkinetic automatisms and poorly organized stereotyped movements.

Application

ELISAIHCWB

Reactivity

HumanMouseRat

Photos