Chemical CompoundsClemizole

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M2582

Brand

No Brand

Description

Clemizole is a H1 histamine receptor antagonist. clemizole hydrochloride can inhibit NS4B’s RNA binding and hepatitis C virus (HCV) replication.clemizole’s antiviral effect is moderate (50% effective concentration of 8 microM against an HCV genotype 2a clone). Combinations of clemizole with either interferon, ribavirin, or the nucleoside (NM283) and nonnucleoside (HCV796) HCV polymerase inhibitors were additive.

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Reactivity

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