COBRA1 Antibody

Brand

Abbiotec

Description

Cofactor of BRCA1 (negative elongation factor B, NELF-B, COBRA1) is an essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. COBRA1 can induce chromatin unfolding.

Application

ELISA

Reactivity

HumanMouseRatRb

Photos